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| Name | Class |
|---|---|
| Florida Biomedical Research Program - James & Esther King | UNKNOWN |
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Despite the deleterious impact of smoking upon cancer treatment outcomes, smoking prevalence remains alarmingly high among cancer patients. Thus, reducing smoking by cancer patients is a public health priority, but treatments to date have demonstrated limited efficacy. Mobile health (mHealth) interventions have the potential to improve treatment efficacy while also greatly extending reach. The goal of this infrastructure proposal is to build a resource to facilitate the creation of mHealth tools that address the tobacco treatment needs of cancer patients. This resource, which will be available to researchers throughout Florida, would fill a critical gap in mHealth capacity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Demonstration Project 1 | No Intervention | Screening and recruitment of cancer patients for connection to evidence-based smoking cessation treatment. The goal of the first demonstration project is to develop a feasible and effective method for screening cancer patients for smoking, determining treatment eligibility, and offering treatment. | |
| Demonstration Project 2 | Experimental | Pilot RCT of Quitline vs. Mobile-Delivered Smoking Cessation Intervention for Cancer Patients. The goal of this pilot feasibility study is two-fold: to evaluate the performance of the platform itself and to provide preliminary data for a future efficacy trial. |
|
| Demonstration Project 3 | No Intervention | Utilizing machine learning to process data obtained from demonstration projects 1 and 2. In Demonstration Project 3, we will utilize all data collected in Demonstration Projects 1 and 2 to conduct machine and deep learning methods. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Quitline Treatment (QT) | Other | Tobacco Free Florida Quitline. 10-week supply of Combination Nicotine Replacement Therapy (NRT). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility: Screening | Our screening process will be deemed feasible if: 1) ≥ 90% of patients complete the screener, 2) the proportion of patients identified as smokers meets or exceeds the historical self-reported proportions at each institution, 3) the program correctly identifies eligible participants and subsequently presents automated advice to quit, 4) it offers an opportunity to enroll in smoking cessation treatment, and 5) ≥ 30% of eligible patients enroll in treatment. | At Baseline |
| Usability: mHealth | Usability will be measured 2 ways: I) ≥ 80% will score ≥ 70 on the Systems Usability Scale (SUS), 10-item measure, (scores 0-100) assessing learnability and usability. II) ≥ 80% rate app as easy to use (dichotomous Y/N). | Up to 6 Months |
| Acceptability/Satisfaction: mHealth | Acceptability/Satisfaction will be measured 4 ways: I) ≥ 80 will score mean ≥ 3.0 Client Satisfaction Questionnaire (CSQ), 8-item measure, (1-4 scale). II) ≥ 80% mostly or extremely satisfied with app. III) ≥ 80% would recommend this app to a friend to quit smoking (dichotomous Y/N). IV) ≥ 80% rate quality of intervention as good or excellent. | Up to 6 Months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Damon Vidrine, DrPH | Moffitt Cancer Center | Principal Investigator |
| Vani Simmons, PhD | Moffitt Cancer Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Miami | Coral Gables | Florida | 33146 | United States | ||
| University of Florida |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42214073 | Derived | Sparrock LS, Vidrine JI, Vinci CE, El Naqa IM, Sutton SK, Salloum RG, Dallery J, Crane TE, Penedo FJ, Brockway SJ, Jones SR, Hoogland CE, Reich RR, Gonzalez-Calderon G, Simmons VN, Vidrine DJ. Creation of an mHealth Infrastructure to Support the Development and Delivery of mHealth Interventions: Protocol for Demonstration Projects Addressing Smoking Cessation in Cancer Care. JMIR Res Protoc. 2026 May 29;15:e92288. doi: 10.2196/92288. |
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| App-based Treatment (mHealth) | Other | Fully automated digitally-delivered smoking cessation intervention targeted to cancer patients. 10-week supply of Combination Nicotine Replacement Therapy (NRT). |
|
| Gainesville |
| Florida |
| 23611 |
| United States |
| Moffitt Cancer Center | Tampa | Florida | 33612 | United States |
| ID | Term |
|---|---|
| D016540 | Smoking Cessation |
| ID | Term |
|---|---|
| D015438 | Health Behavior |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D017216 | Telemedicine |
| ID | Term |
|---|---|
| D003695 | Delivery of Health Care |
| D010346 | Patient Care Management |
| D006298 | Health Services Administration |
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