The goal of this Registry is to see how the device is used when freezing nerves during an amputation procedure.

Inclusion Criteria:

• Patients who have or will have an amputation procedure;
• Patients who are willing and capable of providing informed consent;
• Patients whose age is 18 years or above, or of legal age to give informed consent specific to state and national law.

Exclusion Criteria:

• Women of childbearing potential who are, or plan to become, pregnant during the time of the study;
• Other medical, social, or psychological conditions that in the opinion of the Investigator precludes the subject from appropriate consent or adherence to the protocol.

Subjects who have or will have an amputation procedure.