Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The study is being conducted to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of SHR-3792 injection monotherapy for patients with advanced solid tumors, and to explore the reasonable dosage of SHR-3792 injection monotherapy for patients with advanced solid tumors.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SHR-3792 Injection Group | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| SHR-3792 Injection | Drug | SHR-3792 injection. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maximum tolerated dose (MTD) | From the first dose of study medication up to 21 days. | |
| Recommended phase â…¡ dose (RP2D) | From the first dose of study medication up to 21 days. | |
| Incidence of dose limited toxicity (DLT) | From the first dose of study medication up to 21 days. | |
| Adverse events (AEs) | Up to 24 weeks. | |
| Serious adverse events (SAEs) | Up to 24 weeks. |
| Measure | Description | Time Frame |
|---|---|---|
| Objective response rate (ORR) | Up to 6 months. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Fangfang Peng | Contact | +86-0518-81220121 | fangfang.peng.fp5@hengrui.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shandong First Medical University Affiliated Cancer Hospital | Recruiting | Jinan | Shandong | 250117 | China |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided