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The study is being conducted to evaluate the efficacy and safety of HRS-7535 in subjects with overweight or obesity.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| HRS-7535 Group | Experimental |
| |
| HRS-7535 Placebo Group | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HRS-7535 Tablets | Drug | HRS-7535 tablets. |
| |
| HRS-7535 Placebo Tablets |
| Measure | Description | Time Frame |
|---|---|---|
| The percentage change in body weight relative to the baseline. | The 50th week after administration. | |
| The proportion of participants with a body weight reduction of ≥ 5% relative to the baseline. | The 50th week after administration. |
| Measure | Description | Time Frame |
|---|---|---|
| The proportion of participants with a body weight reduction of ≥ 10% relative to the baseline. | The 50th week after administration. | |
| Adverse events (AEs). | About 52 weeks. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chinese PLA General Hospital | Beijing | Beijing Municipality | 100039 | China |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| Drug |
HRS-7535 placebo tablets. |
|
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |