Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of this retrospective observational study was to describe the epidemiology of Neisseria gonorrhoeae septic arthritis over the last 10 years at Brest and Rennes university hospitals. The main question is whether there are any risk factors based on the epidemiological and clinical data on these cases. The second objective is to characterize the gonococcal strains isolated in order to determine whether there is a common clone, a virulence factor or specific resistance genes.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gonococcal arthritis | Patients with a positive joint sample for Neisseria gonorrhoeae between 06/01/2014 and 06/30/2024 in Brittany, France. |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Age | years | 10 years |
| Date of sampling | DD/MM/YYYY | 10 years |
| Type of sample | joint fluid or joint fluid on blood culture bottle | 10 years |
| Rate of white blood cells | quantification of white blood cells /mm3 | 10 years |
| Sexually transmitted infection | associated or not, if associated, name of STI and localization | 10 years |
| Men who have sex with men | yes or no | 10 years |
| HIV pre-exposure prophylaxis (PreP) | yes or no | 10 years |
| Comorbidities | any history mentioned in the medical file, such as fracture, illness, treatment, chronic alcoholism, cancer, diabetes, etc. | 10 years |
| Imaging | medical conclusion of the ultrasound or radiology performed |
| Measure | Description | Time Frame |
|---|---|---|
| Molecular typing: clone | performed on strains sent to the Centre National de Référence des IST - APHP | 10 years |
| Molecular typing: virulence factors | performed on strains sent to the Centre National de Référence des IST - APHP |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Patients with a Neisseria gonorrhoeae-positive joint sample (from an enrichment vial or a native sample) between 06/01/2014 and 06/30/2024.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Geneviève HERY-ARNAUD | Contact | 0298145107 | +33 | genevieve.hery-arnaud@univ-brest.fr |
| Valentin LEMOINE | Contact | valentin.lemoine@chu-brest.fr |
| Name | Affiliation | Role |
|---|---|---|
| Geneviève HERY-ARNAUD | CHU de Brest | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rennes University Hospital | Recruiting | Rennes | Brittany Region | 35000 | France |
All collected data that underlie results in a publication
Data will be available beginning three years and ending fifteen years following the final study report completion
Data access requests will be reviewed by the internal committee of Brest UH. Requestors will be required to sign and complete a data access agreement
Not provided
Not provided
| ID | Term |
|---|---|
| D006069 | Gonorrhea |
| D007239 | Infections |
| D001170 | Arthritis, Infectious |
| ID | Term |
|---|---|
| D016870 | Neisseriaceae Infections |
| D016905 | Gram-Negative Bacterial Infections |
| D001424 | Bacterial Infections |
| D001423 | Bacterial Infections and Mycoses |
Not provided
Not provided
Not provided
Not provided
Not provided
| 10 years |
| Blood cultures (peripheral blood) | positive or negative | 10 years |
| Time to diagnosis | in days (between onset of symptoms and antibiotics) | 10 years |
| Treatments implemented | name of the probabilistic treatment (antibiotic) and after identification or antibiogram | 10 years |
| Antibiotic sensitivity profile | Susceptibility or resistance according to SIR methodology and, if achieved: minimum inhibitory concentrations of antibiotics tested on the strain in mg/L | 10 years |
| Surgery | yes or not | 10 years |
| Evolution | recovery or relapse | 10 years |
| Rate of neutrophils | proportion of neutrophils in %. | 10 years |
| Rate of CRP (C-reactive protein) | in mg/L | 10 years |
| 10 years |
| Molecular typing: resistance genes | performed on strains sent to the Centre National de Référence des IST - APHP | 10 years |
| CHU de BREST | Recruiting | Brest | 29609 | France |
|
| D015231 | Sexually Transmitted Diseases, Bacterial |
| D012749 | Sexually Transmitted Diseases |
| D003141 | Communicable Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |