The surgical extraction of an impacted tooth is one of the most common procedures in oral surgery. Following extraction, the tissue undergoes repair and regeneration through a process known as socket healing (SH).

SH is a complex and highly regulated biological process. Several local, surgical, and systemic factors can influence SH. This study aimed to evaluate the impact of the magnesium depletion score (MDS) on the socket healing following tooth extraction.

The surgical extraction of impacted teeth is one of the most commonly performed procedures in the field of oral surgery. According to the American Dental Association (ADA), surgical extraction involves "the removal of a tooth that has either erupted or not into the mouth, which includes the removal of a mucoperiosteal flap and the trimming of a portion of the tooth and/or bone." Complications related to post-extraction wound healing-such as pain, swelling, bleeding, and infection-can pose significant challenges for both patients and surgeons. Optimal healing depends not only on the tissue itself but also on various local, surgical, and systemic factors, including but not limited to the patient's stress levels, oral hygiene, age, sex, overall health status, and nutrition, many of which may be beyond intervention or control. Consequently, there is growing interest in treatments that can enhance wound healing. Recent studies indicate that magnesium consumption may have a beneficial effect on the healing process.

Inclusion Criteria:

• Systemically healthy adult participants who were scheduled to undergo surgical extraction of lower impacted third molars.

Exclusion Criteria:

• Refusal to consent
• Presence of chronic diseases
• Use of medications that affect wound healing (steroids, bisphosphonate, or immunosuppressives)
• Prior radiotherapy in the head and neck area
• Pregnancy
• Inability to self-evaluate, and inability to communicate verbally or in writing.

Systemically healthy adult participants from both sexes, who were scheduled to undergo surgical extraction of lower impacted third molars, with a physical status classified as ASA I according to the American Society of Anesthesiologists (ASA).