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The aim of this observational, cross-sectional study is to investigate the relationship between alexithymia and migraine frequency (considering alexithymia a condition that can influence the severity of the clinical phenotype of migraine, favoring its chronicization), in an analysis adjusted for psychiatric comorbidity (for anxiety and depression, potentially influencing migraine chronicization) and for personalogical factor represented by apathy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diagnosis of episodic migraine without or with aura, chronic migraine, and/or MOH | Female patients, aged 12-65 years, diagnosed with episodic migraine without or with aura, chronic migraine, and/or MOH according to the criteria of ICHD-3 2018 |
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| Measure | Description | Time Frame |
|---|---|---|
| Degree of alexithymia | Independent variable measured as a score on the TAS-20 scale | In 3 periods of 30 days each (3 months), which make up the 90-day observation time interval |
| Migraine frequency | In 3 periods of 30 days each (3 months), which make up the 90-day observation time interval |
| Measure | Description | Time Frame |
|---|---|---|
| Number of "drug days" in patients diagnosed with MOH | In 3 periods of 30 days each (3 months), which make up the 90-day observation time interval | |
| Degree of alessithymia in patients diagnosed with MOH | In 3 periods of 30 days each (3 months), which make up the 90-day observation time interval |
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Inclusion Criteria:
Exclusion Criteria:
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Female patients, aged 12-65 years, diagnosed with episodic migraine with or without aura, chronic migraine and/or MOH according to ICHD-3 2018 criteria
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| Name | Affiliation | Role |
|---|---|---|
| Eugenia Rota | Azienda Sanitaria Locale di Alessandria (ASL AL) | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Azienda Sanitaria Locale di Alessandria (ASL AL) | Alessandria | Italy | 15121 | Italy |
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| ID | Term |
|---|---|
| D008881 | Migraine Disorders |
| D000342 | Affective Symptoms |
| ID | Term |
|---|---|
| D051270 | Headache Disorders, Primary |
| D020773 | Headache Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 | Nervous System Diseases |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |