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Identify skull bone Associated Anomalies in patients with cngenital unilatral choanal atresia
Choanal atresia is a rare congenital disorder caused by a failure to develop the posterior nasal cavity (choana), resulting in a missing opening between the nasopharynx and the nasal cavities.It is the most common congenital anatomical abnormality of the nasal cavities with incidence ratio approximately 1/5000-7000 live births
Generally, choanal atresia may affect one or both Choanae, although most studies show that the unilateral form is more common than the bilateral one,and the incidence is higher in females than in males Children with unilateral choanal atresia are subject to unilateral breathing usually have late unilateral nasal obstruction, persistent ipsilateral rhinorrhea, and recurrent rhinosiusitis Previous studies have shown that the ratio of bone to membranous atresia is 9:1; although a detailed review of CT findings with histopathological studies showed that mixed-wall atresia is the most common and is present in 71% of cases, while in 29% of cases we found a pure bone wall Computer tomography (CT) is presently the golden standard in diagnostics of nasal cavity diseases; thus, it can be applied successfully as a tool for assessing anatomical structures
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CT | Device | Thickened Medial Pterygoid Plates In bony atresia, excessive thickening of the medial pterygoid plates is common. Narrowing or Fusion of the Posterior Choanae Complete bony or membranous obstruction at the choanal opening. Abnormal Sphenoid Bone Development Hypoplasia or deformity in the sphenoid sinus, affecting adjacent structures. Vomer Deviation or Hypertrophy The vomer bone is often displaced or abnormally thickened, contributing to obstruction. Abnormal Development of the Hard Palate |
| Measure | Description | Time Frame |
|---|---|---|
| Radiological Variations in Skull Bones in Patients with Congenital Unilateral Choanal Atresia: A Cross-Sectional Study" | Degree and Type of Skull Bone Anomalies Presence and extent of bony abnormalities in the skull base (e.g., sphenoid bone asymmetry, pterygoid plate thickening) Degree of nasal cavity narrowing and choanal obstruction Associated maxillofacial bone abnormalities (e.g., septal deviation, maxillary sinus hypoplasia) 2. Measurement of Specific Skull Bone Changes Thickness of the atretic plate (bony vs. membranous) Asymmetry of pterygoid plates (measured in mm) Deviation angle of the nasal septum (in degrees) Orbital and maxillary asymmetry | 10_12 month |
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Inclusion Criteria:
Exclusion Criteria:
Patients with severe craniofacial syndromes
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The study population will include patients diagnosed with congenital unilateral choanal atresia (CUCA). The inclusion and exclusion criteria will ensure a well-defined and homogenous group for analysis.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed Sayed Moaz, Master | Contact | 0201063390574 | ahmoooodz857@gmail.com | |
| Mohamed Azam Abdelrazek, Professor | Contact |
| Name | Affiliation | Role |
|---|---|---|
| Ahmed Ragab Sayed, Lecturer | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26106591 | Background | Kwong KM. Current Updates on Choanal Atresia. Front Pediatr. 2015 Jun 9;3:52. doi: 10.3389/fped.2015.00052. eCollection 2015. |
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