Silymarin Bioavailability Study

Novel Micellar Formulation of Silymarin with Enhanced Bioavailability in a Double-Blind, Randomized, Crossover Human Trial

This study seeks to evaluate and compare the pharmacokinetics of a novel micellar silymarin formulation with that of a standard silymarin formulation.

Inclusion Criteria:

• Male or female aged 21- 65 years
• Healthy, good physical condition
• Voluntary, written, informed consent to participate in the study.

Exclusion Criteria:

• Serious acute or chronic diseases e.g. liver, kidney, or gastrointestinal diseases
• Contraindication or allergies to milk thistle
• Pregnancy or breastfeeding
• Concurrent use of supplements and/or medications
• Participation in another investigational study