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Parkinson's disease (PD) is a progressive and chronic neurodegenerative disease, which presents signs and symptoms both motor (impaired gait, posture, balance, etc.) and cognitive (memory loss, dementia, etc.), all of which are causing disability and assuming a high economic cost. Currently, there are already certain authors who have shown how a high-intensity interval training (HIIT) protocol produces improvements in cognitive and physical performance in healthy adults6 and in people with multiple sclerosis. However, another modality has been created, such as high-intensity functional training (HIFT), which can benefit different populations, both healthy and pathological, due to the multimodal nature of the exercises. Thanks to multimodality, more aspects such as agility, coordination and precision of movements are worked on compared to unimodal HIIT programs that make this relevant work difficult in a person's daily life. The current study aims to demonstrate the effectiveness of a HIFT training protocol in a specific population, such as people with Parkinson's disease.
The hypothesis is that high-intensity functional training (HIFT), at a motor and cognitive level, provides a greater benefit than conventional programs of strength, balance and cognition, on the functionality and cognitive capacity of people with Parkinson's disease.
Overall objective:
- To assess whether the HIFT training program is associated with significant improvements in functional and cognitive capacity compared to conventional strength, balance and cognition programs in Parkinson's patients.
Secondary objectives:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental group | Experimental | The experimental group will perform a high-intensity functional training program twice a week for 10 weeks. |
|
| Control Group | No Intervention | The control group will continue to carry out their physical and cognitive exercise routine during the week, recording their activity in days and sessions. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| high intensity functional training | Other | The pillar of rehabilitation will be based on high intensity functional training. 45-minute sessions divided into 5 minutes of warm-up, 35 minutes of functional exercises, and 5 minutes of going back to bed and cooling down. The 35 minutes of exercises were divided into 3 categories: lower extremity exercises, upper extremity exercises, and static and dynamic coordination and balance exercises. Each category will consist of 3 exercises per session, performing 2-3 series with a maximum of repetitions of 10-RM. The progression of the load will be progressively increased in weeks 3, 5 and 8 between 40-60% of the 1-RM. |
| Measure | Description | Time Frame |
|---|---|---|
| Short physical performance battery (SSPB) | Functional performance evaluation. | 10 minutes |
| Trail Making Test A y B | Evaluation of visual search, scanning, processing speed, mental flexibility and executive functions. | 15 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| SF-12 Health Questionnaire | Assessing Perceived Quality of Life | 10 minutes |
| Barthel index | Evaluation of the degree of dependence in activities of daily living. |
| Measure | Description | Time Frame |
|---|---|---|
| The Borg Scale | Rating of perceived exertion | 2 minutes |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marta Aguilar RodrÃguez, PHD | Contact | +34-963983855 | 51308 | marta.aguilar@uv.es |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Valencia | Recruiting | Valencia | Valencia | 46010 | Spain |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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Participants will be randomly divided into two groups: experimental group (EG) and control group (CG). The experimental group will perform a HIFT training program and the control group will follow their routine of physical and cognitive exercises, which will be recorded for control purposes.
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|
|
| 10 minutes |
| fall risk assessment scale | Fall Risk Assessment | 5 minutes |
| 2-minute walk test (2-MWT) | Evaluation of functional capacity | 5 minutes |
| Mini Mental State Examination | Assessment of cognitive function | 20 minutes |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |