Early Feeds in Gastroschisis

The GAIN Study: The Gastroschisis And Early Infant Nutrition Study

This study aims to evaluate the feasibility of initiating early feeds in neonates with gastroschisis, a condition where infants are born with their intestines outside the body.

Inclusion Criteria:

• Neonates with presumed simple gastroschisis
• Born at ≥ 34 weeks' gestation
• Hemodynamically stable
• Consented within 48 hours after abdominal closure
• Mothers who are ≥16 years old
• Mothers who speak English or Spanish

Exclusion Criteria:

• Neonates with evidence of complex gastroschisis at time of closure (any ischemic bowel, intestinal perforation, or obvious atresia with mesenteric defect)
• Presence of any major congenital anomalies
• Neonates who are receiving ionotropic medications
• Neonates who are wards of the state
• Neonates whose care is considered to be futile or those undergoing re-direction of care
• Neonates participating in another interventional trial
• Any patient deemed unfit for participation by study investigator(s)