Benefit of Ethanol Sclerotherapy of Endometriomas Before Ovarian Stimulation on Pregnancy Rates in IVF/ICSI

Benefit of Ethanol Sclerotherapy of Endometriomas Before Ovarian Stimulation on Pregnancy Rates in IVF/ICSI

Evaluation of progressive pregnancy rates (with an embryo with cardiac activity at 12 weeks), on a first attempt at IVF/ICSI (fresh and frozen embryo transfers) following the discovery of one or two endometrioma(s) of 30 to 80 mm, without a history of cystectomy, and comparison between the two groups: ethanol sclerotherapy and therapeutic abstention

Inclusion Criteria:

• Infertile women aged 18 to 43,
• Presenting one or 2 endometriotic cysts of 30 mm to 80 mm long axis, confirmed by ultrasound and/or pelvic MRI and without signs of atypia,
• With indication of IVF/ICSI, first IVF/ICSI after the discovery of endometriosis cyst(s),
• Having given their consent.

Exclusion Criteria:

• A history of ovarian cystectomy,
• A non-homogeneous cyst that cannot be punctured (risk of incomplete aspiration),
• Complex adnexal image that cannot exclude an associated hematosalpinx (communicating hematosalpinx, tissue component),
• A recent tubo-ovarian infection,
• An active, untreated vaginal infection,
• Anticoagulant treatment at a therapeutic dose,
• All adult patients protected by law (under guardianship or curatorship),
• Problems understanding the French language,
• Participation in intervention research,
• All patients not affiliated to the social security system.