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This study will be done to investigate the effect of arm cycling on exercise and functional capacity, arterial blood gases, pulmonary functions, diaphragmatic excursion, time to peak inspiratory amplitude, physical function, anxiety, and depression after colectomy in the elderly.
Around 42% of older patients with Chronic Respiratory Disease are considered 'frail', putting them at higher risk of adverse outcomes after surgery. Factors such as poor frailty, high comorbidity, low physical performance, poor nutritional state, or cognitive impairment increase the risk. Postoperative complications, such as pulmonary complications, can lead to increased morbidity, mortality, and hospital stays. Preoperative physiotherapy and exercise interventions have been suggested as preventive solutions. However, many patients undergo emergency surgery, emphasizing the need for strict postoperative care pathways. Exercise interventions, such as upper extremity aerobic exercise, have shown benefits in improving immobilization, oxygen consumption, ventilation, heart rate response, dyspnea, and quality of life. This study aims to investigate the effects of arm cycling on exercise capacity, arterial blood gases, pulmonary functions, diaphragmatic excursion, anxiety, and depression after colectomy in the elderly.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Arm cycling exercise | Experimental | The study group, including 30 participants, will do 20 minutes of arm cycling exercise plus the traditional physical therapy program. |
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| traditional physical therapy | Active Comparator | The control group, including 30 participants, will do the traditional physical therapy program only |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Arm cycling exercise | Other | The study involves a 20-minute arm cycling exercise twice daily for five days, starting with a warming-up and ending with a cooling-down. The workload is gradually increased to 60-70% of maximal heart rate, with patients sitting on a back support chair with 20 degrees backward inclination. |
| Measure | Description | Time Frame |
|---|---|---|
| Assessing the change of forced vital capacity using spirometry | It will be conducted noninvasively using a spirometer, measuring: forced vital capacity (FVC) in Litres is known as total exhaled volume. | At baseline Day 1 and at the day 5 post-operative |
| Assessing the change of forced expiratory volume in 1 second using spirometry | It will be conducted noninvasively using a spirometer, measuring: forced expiratory volume in 1 second (FEV1) in liters is known as volume exhaled in the first second. | At baseline day 1 and at the day 5 post-operative |
| Assessing The ratio of FEV1 and FVC (FEV1/FVC) | It is a Pulmonary Function measurement that evaluates the Pulmonary Functions | at Baseline Day 1 and at the day 5 Postoperative |
| Assessment of change of diaphragmatic excursion using ultrasonography | Participants undergo ultrasonography to measure diaphragmatic excursion In centimeters (cm) . The measurement will be performed using a 1- to 5-MHz ultrasound transducer in M-mode. | At baseline and at the day 5 post-operative |
| Assessment of change of diaphragmatic Function using ultrasonography | Participants undergo ultrasonography to measure the Time-to-peak inspiratory amplitude (TPIAdia) of the diaphragm during tidal breathing in seconds (sec) of each hemidaphragm ( right and left ). The measurement will be performed using a 1- to 5-MHz ultrasound transducer in M-mode. | At baseline and at the day 5 post-operative |
| Assessment of change of functional capacity | A 6-minute stepper test is proposed to evaluate exercise tolerance using a standardized protocol. The test measures the number of steps performed on a stepper in 6 minutes, equivalent to the 6-minute walk test. Patients are accustomed to the stepper for 2 minutes, followed by a 3-minute rest and 6-minute stepping period. Heart rate and oxygen saturation are monitored, and an investigator stays behind the patient throughout the test. |
| Measure | Description | Time Frame |
|---|---|---|
| Assessment of change of potential of partial pressure of oxygen | Arterial geometry will be used to examine the effect of cycling exercise on gas exchange, including the potential of partial pressure of oxygen (PaO₂) in millimeters of mercury (mmHg) | At baseline and at the day 5 post-operative |
| Assessment of change of partial pressure of carbon dioxide (PaCO₂) |
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Inclusion Criteria:
Exclusion Criteria:
Men who will meet one of the following criteria will be excluded:
Sixty male patients who received a surgical removal of a diagnosed colon cancer (i.e., including right, transverse, left, sigmoid, subtotal, total, and hemicolectomy) will be included.
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| Name | Affiliation | Role |
|---|---|---|
| Israa Youssef | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| King Hamad University Hospital, | Al Muharraq | Bahrain |
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A Prospective Randomised Controlled Trial
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| The traditional physical therapy program | Other | The patient undergoes 10 minutes of deep diaphragmatic breathing exercises, 10 minutes of spirometer training, 3-set ankle pump and heel slide exercises, 10-minute sitting on the bed edge, 5 minutes of walking in the intensive care unit, and 3-set active free range of motion exercises. |
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| At baseline and at the day 5 post-operative |
Arterial geometry will be used to examine the effect of cycling exercise on gas exchange, including the partial pressure of carbon dioxide (PaCO₂) in millimeters of mercury (mmHg). |
| At baseline and at the day 5 post-operative |
| Assessment of change of potential of hydrogen (PH) | Arterial geometry will be used to examine the effect of cycling exercise on gas exchange, including the potential of hydrogen (PH) | At baseline and at the day 5 post-operative |
| Assessment of change of bicarbonate (HCO₃) | Arterial geometry will be used to examine the effect of cycling exercise on gas exchange, including the bicarbonate (HCO₃) in millimoles per liter (mmol/L) | At baseline and at the day 5 post-operative |
| Assessment of change of lactate | Arterial geometry will be used to examine the effect of cycling exercise on gas exchange, including the lactate millimoles per liter (mmol/L). | At baseline and at the day 5 post-operative |
| Assessment of change of physical function in intensive care unit tested scored (PFIT) | Physical function in intensive care test score (PFIT)-s will be used to assess physical function, consisting of four components: 1-assistance, 2-marching, 3-shoulder flexion strength, and 4-knee extension strength. The strength was based on the Oxford grading system, with each component mentioned above scoring 0-3 and summed to a maximum ordinal score of 12 points, Ranging from 0-12 with a higher score reflecting a better physical function. | At baseline and at the day 5 post-operative |
| Assessment of change of anxiety (HAD scale ) | The Hospital Anxiety and Depression Scale will be used. it is a 14-item self-report screening scale with 7 items each for anxiety. A score of 0-7 is considered normal; 8-10 indicates mild illness, 11-15 moderate illness, and scores 16-21 are suggestive of severe illness | At baseline and at the day 5 post-operative |
| Assessment of change of depression ( HAD scale ) | The Hospital Anxiety and Depression Scale will be used. it is a 14-item self-report screening scale with 7 items each for depression. A score of 0-7 is considered normal; 8-10 indicates mild illness, 11-15 moderate illness, and scores 16-21 are suggestive of severe illness | At baseline and at the day 5 post-operative |
| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
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