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This study was a target trial emulation using the National Health Claims database established by the Korean National Health Insurance Service (K-NHIS). 8,325 patients were included.
Among these patients, any patients who were prescribed SAPT or DAPT at the date of discharge from the index hospitalization for standard EVAR were defined as being in the SAPT group (N=4,162) and the DAPT group (N=4,163), respectively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Dual antiplatelet therapy | Patients who were prescribed dual antiplatelet therapy at the date of discharge from the index hospitalization for standard EVAR | ||
| Single antiplatelet therapy | Patients who were prescribed single antiplatelet therapy at the date of discharge from the index hospitalization for standard EVAR |
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| Measure | Description | Time Frame |
|---|---|---|
| Major adverse cardiac and cerebrovascular events (MACCE) | composite of all-cause death, myocardial infarction (MI), or ischemic stroke | 1 year after EVAR |
| Major or clinically relevant non-major bleeding | Diagnostic codes in the primary or secondary position and transfusion receipt | 1 year after EVAR |
| Re-intervention or surgery for AAAs | Re-intervention or surgery for AAAs | 1 year after EVAR |
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Inclusion Criteria:
Exclusion Criteria:
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All patients who underwent EVAR for AAA and were successfully discharged and prescribe any antiplatelet therapy.
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41065286 | Derived | Choi KH, Kang D, Nam J, Park TK, Song MG, Seo TS, Yang WJ, Choi SH. Efficacy and Safety of Antiplatelet Therapy After Endovascular Aortic Repair: A Target Trial Emulation. J Am Heart Assoc. 2025 Oct 21;14(20):e044102. doi: 10.1161/JAHA.125.044102. Epub 2025 Oct 9. |
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| ID | Term |
|---|---|
| D017544 | Aortic Aneurysm, Abdominal |
| ID | Term |
|---|---|
| D001014 | Aortic Aneurysm |
| D000783 | Aneurysm |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| D001018 |
| Aortic Diseases |