The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.

Inclusion Criteria:

• being ASA1-2 status
• between the ages of 18-70
• who are planned for laparoscopic cholecystectomy

Exclusion Criteria:

• Patients who refuse to give informed consent
• Pregnant and breastfeeding patients
• Morbidly obese patients (Body mass index over 40)
• Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability
• Patients using drugs known to prolong myocardial repolarization
• inability to increase SPO2 above 95 despite necessary intervention