Low and Moderete Flow Anaesthesia on Haemodynamics

The Comparison of the Effects of Low and Medium Flow Anesthesia on Haemodynamics, Arrhytmia Risk and Cerebral Oxygenation in Laparoscopic Cholecystomy Cases

The study topic investigates the potential advantages of low-flow anesthesia in terms of physiological protection and resource saving.

The study aims to compare the effects of low and normal flow sevoflurane anesthesia on the frontal QRS-T angle and cerebral oxygenation in laparoscopic cholecystectomy surgery. The primary objective was to evaluate the effects of low-flow anesthesia on hemodynamic stability and arrhythmia risk; the secondary objective was to compare the total sevoflurane consumption in both methods.

Inclusion Criteria:

• being ASA1-2 status
• between the ages of 18-70
• who are planned for laparoscopic cholecystectomy

Exclusion Criteria:

• Patients who refuse to give informed consent
• Pregnant and breastfeeding patients
• Morbidly obese patients (Body mass index over 40)
• Patients with uncontrolled diabetes mellitus, with serious cardiovascular, pulmonary, renal, hepatic disease, obstructive sleep apnea, with electrolyte imbalance- Those with a history of alcohol or drug abuse, with perioperative hemodynamic instability
• Patients using drugs known to prolong myocardial repolarization
• inability to increase SPO2 above 95 despite necessary intervention