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The aim of this study was to compare the effectiveness of chlorhexidine versus saline in flushing the surgical area during colorectal cancer surgery. The primary outcomes included surgical site infection, postoperative complication rates, et al.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diabetic rectal cancer patients, chlorhexidine irrigation group | Experimental | After colorectal cancer surgery, flush the surgical area with chlorhexidine solution 1 minute before suturing the skin. |
|
| Diabetic rectal cancer patients, saline irrigation group | No Intervention | ||
| Diabetic colon cancer patients, chlorhexidine irrigation group | Experimental |
| |
| Diabetic colon cancer patients, saline irrigation group | No Intervention | ||
| Non-diabetic rectal cancer patients, chlorhexidine irrigation group | Experimental |
| |
| Non-diabetic rectal cancer patients, saline irrigation group | No Intervention | ||
| Non-diabetic colon cancer patients, chlorhexidine irrigation group | Experimental |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intraoperative area irrigation | Procedure | After colorectal cancer surgery, flush the surgical area with chlorhexidine solution 1 minute before suturing the skin. According to abdominal cavity contamination, bleeding and tumor invasion to determine the flushing time and flush fluid volume. If the abdominal cavity infection is more serious or exudate more, the flushing time can be relatively prolonged. At last, there were no obvious blood residue, tissue fragments and suppurative secretions in abdominal cavity. Ensure that the surgical field of vision is clear, the surface of each organ is smooth, and there is no abnormal exudate. |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with Surgical site infection within 30 days | Any surgical site infection within 30 days of surgery is classified as superficial incision, deep mouth, or organ space infection according to the U.S. Centers for Disease Control and Prevention standards. | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with Postoperative complication within 30 days | Including anastomotic fistula, anastomotic hemorrhage, intestinal obstruction, deep vein thrombosis and so on | 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Nanchong Central Hospital | Recruiting | Nanchong | Sichuan | 637000 | China |
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| ID | Term |
|---|---|
| D015179 | Colorectal Neoplasms |
| D013530 | Surgical Wound Infection |
| ID | Term |
|---|---|
| D007414 | Intestinal Neoplasms |
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
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|
| Non-diabetic colon cancer patients, saline irrigation group | No Intervention |
|
| D009369 | Neoplasms |
| D004066 | Digestive System Diseases |
| D005767 | Gastrointestinal Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D012002 | Rectal Diseases |
| D014946 | Wound Infection |
| D007239 | Infections |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |