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| Name | Class |
|---|---|
| LAPEF laboratory, Sao paulo | UNKNOWN |
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Overweight and obesity, particularly increased total and/or abdominal fat mass (FM), are strongly linked to the development of cardiovascular diseases. Managing obesity effectively requires lifestyle and dietary modifications, including increased physical activity. Among the various exercise strategies, Moderate-Intensity Continuous Training (MICT) and High-Intensity Interval Training (HIIT) are widely recommended for reducing FM. Compared to MICT, HIIT is a time-efficient approach, often perceived as more enjoyable, and has been shown to promote greater total and abdominal fat loss in a shorter period. However, the precise mechanisms underlying this enhanced fat loss remain unclear.
This study aims to compare the acute effects of two isoenergetic exercise sessions - MICE (Moderate-Intensity Continuous Exercise) and HIIE (High-Intensity Interval Exercise) - on key physiological responses involved in fat mass loss. Specifically, we will assess plasma catecholamine levels during exercise and recovery, as well as oxygen consumption, substrate oxidation, and appetite over the 2-hour post-exercise period in young females with overweight or obesity. By elucidating the role of catecholaminergic stimulation as a potential regulator of fat mass loss, this research could provide valuable insights for optimizing exercise strategies in weight management and metabolic health.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High Intensity Interval Exercise | Experimental | High Intensity Interval Exercise: 5 minutes of WarmUp + 10 x (1 minute at 85% HRmax followed by 1 minute of recovery at a power equivalent to 40% of HRmax) |
|
| Moderate Intensity Continuous Exercise | Experimental | Moderate Intensity Continuous Exercise: 5 minutes of WarmUp + 35 minutes at 55% HRmax |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Exercise | Other | Two Exercise Modalities: HIIE and MICE |
|
| Measure | Description | Time Frame |
|---|---|---|
| Oxygen consumption during exercise and the recovery period | Determination of oxygen consumption during exercise and 2 hours after the exercise session (HIIE and MICE). Determination from Metamax (3D Cortex). | Measurement at rest for 20 minutes, then during warm-up for 10 minutes, then during exercise for 20 minutes and finally during 2 hours after the end of the exercise. |
| Measure | Description | Time Frame |
|---|---|---|
| Lipid before and after the exercise. | Determination of lipid oxidation before and after the exercise. Lipid oxidation is measured from oxygen and carbon dioxide consumption (Metamax 3D Cortex). | Measurement at rest for 20 minutes and then during 2 hours after the end of the exercise. |
| Carbohydrate before and after the exercise. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Laboratório de Fisiologia e Metabolismo Aplicados à Educação FÃsica | Recruiting | São Paulo | São Paulo | 475 | Brazil |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31524825 | Background | Dupuit M, Rance M, Morel C, Bouillon P, Pereira B, Bonnet A, Maillard F, Duclos M, Boisseau N. Moderate-Intensity Continuous Training or High-Intensity Interval Training with or without Resistance Training for Altering Body Composition in Postmenopausal Women. Med Sci Sports Exerc. 2020 Mar;52(3):736-745. doi: 10.1249/MSS.0000000000002162. | |
| 32881054 |
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Data collected on the volunteers will be made anonymous.
Determination of carbohydrate oxidation before and after the exercise. Carbohydrate oxidation is measured from oxygen and carbon dioxide consumption (Metamax 3D Cortex). |
| Measurement at rest for 20 minutes and then during 2 hours after the end of the exercise. |
| Catecholamines | Determination of cathecolamines concentration in blood during exercise and 2 hours after the end of the exercise. | 5 collections: before exercise started, at the end of exercise (exercise duration is 20-35 minutes), at 30 minutes, 60 minutes and 120 minutes after the end of exercise |
| Energy intakes 24 hours after the exercise | Evaluation of energy intakes after the exercise session (HIIE vs MICE). Exercise session finish at 11:30 a.m. After that, at home, participants have to complete by themselves a food-record on which they will describe all their meal during 24 hours after the end of the exercise session. It includes their lunch, dinner and their breakfast the next morning. | 24 hours post exercise |
| Dupuit M, Boscaro A, Bonnet A, Bouillon P, Bruno P, Morel C, Rance M, Boisseau N. Acute metabolic responses after continuous or interval exercise in post-menopausal women with overweight or obesity. Scand J Med Sci Sports. 2020 Dec;30(12):2352-2363. doi: 10.1111/sms.13814. Epub 2020 Sep 18. |
| 25747467 | Background | Cunha FA, Midgley AW, McNaughton LR, Farinatti PT. Effect of continuous and intermittent bouts of isocaloric cycling and running exercise on excess postexercise oxygen consumption. J Sci Med Sport. 2016 Feb;19(2):187-92. doi: 10.1016/j.jsams.2015.02.004. Epub 2015 Feb 23. |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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