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| Name | Class |
|---|---|
| Cerballiance | UNKNOWN |
| Roche Diagnostic Ltd. | INDUSTRY |
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Heart failure poses a significant public health challenge due to its high prevalence and the substantial human and financial costs it generates. Furthermore, the lack of clear screening guidelines and challenges in accessing care and multi-professional coordination, contribute to diagnostic delays, leading more patients to seek care in more severe clinical states and requiring direct admission to emergency departments. There is therefore also a major organizational challenge in better managing the entry of patients into the healthcare system. This necessitates the development of structured heart failure screening strategies.
The 2021 European Society of Cardiology (ESC 2021) guidelines on heart failure screening prioritize the identification of at-risk individuals and the early detection of disease manifestations. They suggest that, in high-risk groups, tests such as echocardiography and biomarker measurement (NT-proBNP) should be used to detect heart failure at an early stage, even in the absence of symptoms. The guidelines also delineate specific biomarker thresholds and propose organizational frameworks with defined timelines to facilitate systematic screening.
The implementation of a heart failure screening pathway within primary care involving multi-professional cooperation is therefore warranted.
Stratifying screening based on risk factors and symptomatology is expected to enhance the positive predictive value of the screening process. Furthermore, evaluating the efficacy of this pathway is crucial for establishing a standardized, reproducible clinical protocol suitable for routine primary care practice.
This study is a prospective, multicenter, observational study conducted within the context of routine clinical care.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients participating in the heart failure screening pathway in general medicine consultations |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Heart failure screening pathway | Other | Heart failure screening pathway in general medicine consultations (questionnaire, NT-proBNP level, echocardiographic examination) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Rate of patients with a confirmed diagnosis of heart failure | i.e. patients with at least one "yes" box checked in "step 1" and "step 2" of the questionnaire, with an NT-proBNP level ≥ 125 pg/ml, and an echocardiographic examination performed by the cardiologist confirming a diagnosis of HF according to the 2021 ESC guidelines. | 2 months |
| Rate of patients with an unconfirmed diagnosis of heart failure | i.e. all of the following patients:
| 2 months |
| Rate of patients with an indeterminate diagnosis of heart failure | Absence of all diagnostic criteria. | 2 months |
| Measure | Description | Time Frame |
|---|---|---|
| Risk factors for heart failure | Day 1 | |
| Presence of dyspnea | Evaluation of the main symptoms of heart failure. | Day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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Patients aged 65 years or older participating in the heart failure screening pathway in general medicine consultations
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| Name | Affiliation | Role |
|---|---|---|
| Jean-Michel TARTIERE, MD | Centre Hospitalier Intercommunal Toulon La Seyne sur Mer | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Maison de Santé Pluridisciplinaire La Cadière d'Azur | La Cadière-d'Azur | Var | 83740 | France | ||
| Maison de Santé Pluridisciplinaire La Farlède |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| Weight gain |
Evaluation of the main symptoms of heart failure. |
| Day 1 |
| Presence of edema | Evaluation of the main symptoms of heart failure. | Day 1 |
| Presence of fatigue | Evaluation of the main symptoms of heart failure. | Day 1 |
| La Farlède |
| Var |
| 83210 |
| France |
| Maison de Santé Pluridisciplinaire Caduceus | La Seyne-sur-Mer | Var | 83500 | France |
| Maison de Santé Pluridisciplinaire Beaussetanne | Le Beausset | Var | 83330 | France |
| Maison de Santé Pluridisciplinaire Vallée du Gapeau - Sollies-Pont | Solliès-Pont | Var | 83210 | France |
| Maison de Santé Pluridisciplinaire Toulon City | Toulon | Var | 83000 | France |