This study aims to investigate the impact of supplementation with two different doses of Rosemary and Daylily herbal extract on various health outcomes in middle-aged adults. Over an eight-week period, the trial will assess improvements in sleep quality, circadian rhythms, energy metabolism, and relevant biochemical markers. The study employs a randomized, placebo-controlled, crossover design to evaluate the efficacy of these supplements in enhancing overall health and well-being.

Inclusion Criteria:

• Age > 50 years
• Trouble falling asleep > 5 times a month (NHANES criteria)
• Body mass index 18.5-29.9 kg/m2
• Free of major chronic diseases or acute disorders
• Given written informed consent

Exclusion Criteria:

• History of dietary supplement use > 2 weeks before the study commences
• Abnormal values for lab clinical chemistry (> 2 SD)
• Unwillingness to return for follow-up analysis
• Participation in other clinical trials
• Moderate-to-heavy use of alcohol (> 3 drinks per week)

Data obtained through this study may be provided to qualified researchers with academic interest in sleep medicine. Data will be coded, with no PHI included. Approval of the request and execution of all applicable agreements are prerequisites to the sharing of data with the requesting party.

Data requests can be submitted starting 9 months after article publication and the data will be made accessible for up to 24 months. Extensions will be considered on a case-by-case basis.

Only qualified researchers with academic interest in sleep medicine