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Adhesive Intestinal obstruction is an inevitable complication of abdominal surgery with significant morbidity associated with poor quality of life and predispose to repeated hospitalization. Most of them (73% - 90%) can be managed conservatively.Despite advances in surgery, 15to 30% require surgical intervention primarily or due to failure of conservative management. Because of the nature of the disease recurrence has been estimated to be 30%.Many attempts to prevent formation of postoperative adhesions have been tried. In this trial, we will study the effect of corticosteroids and FFP in prevention of adhesive small bowel obstruction recurrence for follow up of 2 years duration.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group I: adhesive intestinal obstruction | Active Comparator |
| |
| group II: adhesive intestinal obstruction | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| intra-abdominal instillation of corticosteroids | Procedure | after adhesiolysis, peritoneal lavage with diluted corticosteroids will be instillated intra-abdominally |
|
| Measure | Description | Time Frame |
|---|---|---|
| intestinal obstruction | intestinal obstruction is detected if the patient had constipation and vomiting with ultrasound showing dilated bowel and to and fro movement and the plain erect shows multiple air fluid levels | from 1 day to 2 years post operative |
| bowel injury | bowel injury will be detected if intestinal contents present in the drain or wound | from 1 day to 2 years post operative |
| wound infection | wound infection is detected if there is pus in the drain or wound | from 1 day to 2 weeks post-operative |
| Measure | Description | Time Frame |
|---|---|---|
| age | age will be recorded in years | from 2 to 3 days before surgery |
| sex | The sex of the patient will be recorded (male or female) | from 2 to 3 days before surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine | Zagazig | Sharqia Province | 44519 | Egypt | ||
| Zagazig University Hospitals |
data will be available on demand by contacting the principle investigator
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| intra-abdominal instillation of fresh frozen plasma | Procedure | after adhesiolysis, peritoneal lavage with diluted FFP will be instillated intra-abdominally |
|
| Zagazig |
| zagazig |
| 44519 |
| Egypt |
| ID | Term |
|---|---|
| D000267 | Tissue Adhesions |
| ID | Term |
|---|---|
| D002921 | Cicatrix |
| D005355 | Fibrosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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