Magnetic Resonance Imaging in Patients with Trigeminal Neuralgia

Study on Brain Function and Structural Changes in Patients with Trigeminal Neuralgia Based on Magnetic Resonance Imaging.

This study intends to use MRI technology to analyze the dynamic changes and microstructure changes of the brain network in patients with trigeminal neuralgia, evaluate the blood-brain barrier and water exchange rate, and further analyze their correlation with clinical indicators, so as to explore the changes in brain structural plasticity and potential neural mechanisms

Inclusion Criteria:

• The diagnosis was TN according to the ICHD.
• Patients requiring surgical treatment due to ineffective or intolerant treatment with carbamazepine or oxasepine before operation;
• First surgical treatment;
• Right-handed dominant;
• There was no significant loss of sensation

Exclusion Criteria:

• Secondary TN;
• Associated with other types of chronic pain or neuropsychiatric disorders;
• History of head trauma or stroke or cerebrovascular ischemia;
• History of microvascular decompression or other treatments (gamma knife radiosurgery, etc.);
• Unable to cooperate independently;
• Contraindications, such as uncontrolled infection, coagulopathy, etc.;
• MRIcontraindications (e.g., pacemaker, claustrophobia, etc.)