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The Pennington Generation Cohort is an observational study comprised of Louisiana families. Families will be assessed at baseline for a variety of traits and behaviors, and then followed up over time to try to understand the role of lifestyle and the environment on the risk of developing obesity and other health outcomes.
Pennington Biomedical's Greaux Healthy initiative partners with communities to grow healthier generations by expanding the access and reach of Pennington Biomedical's evidence-based practices for the prevention and treatment of childhood obesity. As part of Greaux Healthy, the Pennington Generation Cohort will help evaluate the impact of the program. A sample of up to 1,500 children and adolescents and their families will be recruited from throughout Louisiana. An initial physical exam will establish a baseline for each family with respect to lifestyle behaviors, genetics, and body size/composition. This longitudinal cohort will also assess the association between participation in several childhood obesity prevention and treatment programs and subsequent obesity and related health outcomes. Members of the longitudinal cohort will be followed in the future through clinical visits, questionnaires, and through optional linkages to electronic medical records and administrative databases such as the National Death Index, Social Security Death Master File, and health registry data.
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| Measure | Description | Time Frame |
|---|---|---|
| Obesity | The development of obesity, defined using BMI z-scores during childhood, and BMI during adulthood. | From enrollment up to 20 years of follow-up. |
| Measure | Description | Time Frame |
|---|---|---|
| Weight change | Change in body weight. | From enrollment up to 20 years of follow-up. |
| Mortality | Data from the Pennington Generation Prospective Cohort will be prospectively linked to the National Death Index for the ascertainment of mortality. |
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Inclusion Criteria:
Exclusion Criteria:
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Adults of child-bearing age who are planning to become pregnant, expectant parents, as well as children, adolescents, and young adults and their nuclear family members will be recruited.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Peter T Katzmarzyk, PhD | Contact | 225-763-2536 | peter.katzmarzyk@pbrc.edu | |
| Kara Denstel, PhD | Contact | 763-2614 | kara.denstel@pbrc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Peter T Katzmarzyk, PhD | Pennington Biomedical Research Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pennington Biomedical Research Center | Recruiting | Baton Rouge | Louisiana | 70808 | United States |
A de-identified individual-level dataset will be made available to researchers making a reasonable request to the principal investigator.
Data will be made available 1 year after publication of the primary outcomes manuscript.
Upon reasonable request to the principal investigator and in alignment with the goals of the IRB-approved protocol.
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D001519 | Behavior |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
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Saliva
| From enrollment up to 20 years of follow-up.. |
| Cancer incidence | Data from the Pennington Generation Prospective Cohort will be prospectively linked to the Louisiana Tumor Registry for the ascertainment of incident cancer. | From enrollment up to 20 years of follow-up.. |
| D009750 |
| Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |