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The executive dysfunctions are a problem in individuals with MCI which predict conversion to dementia and is positively related to physical activity level. Previous studies found that exercise can prevent executive and physical dysfunctions for people with MCI. However, the motivation is a critical factor in supporting a sustainable exercise. Exergame is combination of exercise and video game. Enjoyment during playing an exergame can support the exercise motivation. Therefore, we will explore the feasibility of using MR exergame in people with MCI.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Mild cognitive impairment | Experimental |
| |
| Healthy older adults | Other |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mixed reality exergame | Other | The participants will play the Balloon Popping game using Hololens2 (Mixed reality glasses) for one hour. The objective of this game will be to pop all the virtual balloons, focusing on training different executive functions such as inhibitory control and cognitive flexibility. When a participant raises a finger in the air, a virtual needle will appear. After that, the participant will move their finger towards a balloon. Successful contact with a balloon will be indicated by the sound of a pop and the visual effect of confetti. |
| Measure | Description | Time Frame |
|---|---|---|
| Visual attention and task switching | Trail Making Test | before and immediately after intervention |
| Inhibitory control | Color-Word Stroop Test | before and immediately after intervention |
| Single-task performance | Box and Block Test | before and immediately after intervention |
| Dual-task performance | Box and Block with Serial Sevens Test | before and immediately after intervention |
| Cortical outcomes | Transcranial magnetic stimulation was used for measuring the cortical outcomes, which consist of resting motor threshold, input-output curve of motor evoked potentials recruitment and cortical silent period. | before and immediately after intervention |
| Usability | System usability scale questionnaire was used for measuring the usability of mixed reality exergame. It consists of 10-item, which are typically rated on a five-point scale. A higher SUS score generally indicates better usability. | immediately after Mixed reality exergaming |
| Motivation | Intrinsic Motivation Inventory was used for measuring the motivation. It rated on seven-point scale. Higher IMI scores reflect higher levels of motivation. | immediately after Mixed reality exergaming |
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Inclusion Criteria
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Physical Therapy, Mahidol University | Salaya | Changwat Nakhon Pathom | 73170 | Thailand |
We will share IPD when we receive the consent from participants.
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| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D004522 | Educational Status |
| ID | Term |
|---|---|
| D012959 | Socioeconomic Factors |
| D011154 | Population Characteristics |
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| Education | Other | The participants will seat on a chair and watch video clip about MCI and dementia for one hour. |
|
| Adverse side effects | Cybersickness in Virtual Reality Questionnaire was used for assessing cybersickness symptoms, including nausea, vestibular, and oculomotor. The total score is the sum of the three sub-scores. Each question is presented on a 7-item Likert Scale. | immediately after Mixed reality exergaming |