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In recent years, GLP-1 medications have become a widely employed approach by physicians to address weight concerns in patients and lead to weight loss. Little is known, however, about how these medications may alter an individual's attitude towards food, food reactivity, or the specific types and amounts of foods an individual will choose. The purpose of this study is to observe the changes an individual experiences in their relationship and reaction to food and in their food selection prior to or within the first two weeks of taking GLP-1 medication to after three months on the medication. The researchers of this study believe that an understanding of such changes can inform questions seeking to ensure maintenance of appropriate nutrient balance within individuals on weight loss medications.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| GLP-1 Medication Initiation | Other | One visit before starting GLP-1 medication and one visit 3 months after. No other changes administered between visits. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in Total Weight of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months | |
| Change from Baseline in Total Calories of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months | |
| Change from Baseline in Energy Density of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months | |
| Change from Baseline in Variety of Food Selected in the VR Buffet at 3 Months | Baseline and 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Baseline Weight Watchers Food Noise Score at 3 Months | Based on participant's answers to the WW Food Noise questionnaire; Scale of 1-5, 1 being strongly disagree and 5 being strongly agree; Higher scores mean more food noise | Baseline and 3 months |
| Change in Baseline 9-question External Food Cue Responsiveness Questionnaire Score at 3 Months |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Baseline BMI at 3 Months | Calculated from height and weight collected at the end of both sessions | Baseline and 3 months |
Inclusion Criteria:
Exclusion Criteria:
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Participants will be identified from a list of medical patients prescribed GLP-1 medication by their physicians (located in offices near State College or Hershey, PA) and who volunteered to be contacted regarding studies they are eligible for.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Christina M Blackmon | Contact | 425-499-8049 | cmb8633@psu.edu |
| Name | Affiliation | Role |
|---|---|---|
| Travis Masterson | The Pennsylvania State University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Health, Ingestive Behavior, and Technology Laboratory of Pennsylvania State University | Recruiting | State College | Pennsylvania | 16802 | United States |
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| ID | Term |
|---|---|
| D015431 | Weight Loss |
| D005518 | Food Preferences |
| ID | Term |
|---|---|
| D001836 | Body Weight Changes |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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Answers are on a 1-4 scale with 1 being "Rarely" and 4 being "A lot"; higher scores suggest more external food cue reactivity |
| Baseline and 3 months |
| Change in Baseline Adult Eating Behavior Score at 3 Months | Answers on a 1-5 scale with 1 being "Strongly disagree" and 5 being "Strongly agree"; 8 subscales, high scores indicate greater expression of subscale measure | Baseline and 3 months |
| Change in Baseline Three-Factor Eating Questionnaire Score at 3 Months | Rated on a scale of 1-4 with 1 being "Definitely false" and 4 being "Definitely true"; 3 subscales, higher scales on each means greater expression of that behavior | Baseline and 3 months |
| Change in Baseline General Food Craving-Trait Scale Score at 3 Months | Rated on a 0-5 scale with 0 being "Never/not applicable" and 5 being "Always"; higher scores mean more food dependent | Baseline and 3 months |
| Change in Baseline Buffet Food Liking Scores at 3 Months | Rated on a 0-100 scale with 0 being "Dislike extremely" and 100 being "Like extremely"; high scores mean greater liking of the food | Baseline and 3 months |
| D005247 | Feeding Behavior |
| D001519 | Behavior |