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The effect of both the mechanical treatment and the topical metronidazol in reduccing the inflammation and depth of the periodontal pockets were assessed on the first bicuspids.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Metronidazole | Experimental | These periodontal pockets will be treated with a metronidazole-based gel |
|
| Carbopole | Sham Comparator | These deep periodontal pockets (>4mm) are treated with a placebo gel made of carbopol gel |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Root scaling | Procedure | Scaling and root planing is a deep cleaning below the gumline used to remove plaque and tartar that cover the root in the periodontal pockets. This intervention is carried out in both control and experimental sites |
| Measure | Description | Time Frame |
|---|---|---|
| Probing depth | Probing depth is assessed at 6 points around the first bicuspids (mesiovestibular, midvestibular, distovestibular, mesiolingual, midlingual, distolingual) | Both one month and three months after root scaling |
| Mieloperoxidase ng/mL | The determination of the quantity of mieloperoxidase ng/mL was assessed from the crevicular fluid of the treated bicuspids | Both one and three months after root scaling |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Javier Montero, Main Researcher | University of Salamanca | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Dental School of the Faculty of Medicine | Salamanca | Salamanca | 37007 | Spain |
This work is planned to be a PhD dissertation and we are not sure if sharing data would hamper the originality of the future thesis
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| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D010514 | Periodontal Pocket |
| ID | Term |
|---|---|
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D010518 | Periodontitis |
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| ID | Term |
|---|---|
| D012534 | Dental Scaling |
| D005782 | Gels |
| ID | Term |
|---|---|
| D003777 | Dental Prophylaxis |
| D010517 | Periodontics |
| D003813 | Dentistry |
| D011313 | Preventive Dentistry |
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| Topical Gel | Drug | A gel (experimental: metronidazole VS control: carbopol) is introduced in the recently cleaned periodontal pocket. The allocation of either experimental or control gel was distributed randomly, being masked both the patient and the clinician. |
|
| D003102 |
| Colloids |
| D045424 | Complex Mixtures |
| D004304 | Dosage Forms |
| D004364 | Pharmaceutical Preparations |