This study aims to compare the neuromuscular blockade responses in patients undergoing elective surgery under general anesthesia, with a focus on the use of statins. The study will assess the depth of neuromuscular blockade, recovery time, and postoperative residual curarization using Train-of-Four (TOF) monitoring, with the primary goal of determining whether statin use alters the neuromuscular blockade management.

Inclusion Criteria:

• Age 18-75 years
• ASA classification I, II, III
• BMI 18-30
• Statin use for at least 3 months or no prior statin use
• Elective surgery requiring general anesthesia with endotracheal intubation
• Signed informed consent for participation in the study

Exclusion Criteria:

• ASA classification IV or higher
• BMI <18 or >30
• History of liver or renal insufficiency (creatinine >1.6, liver function tests >2x normal)
• Neuromuscular, psychiatric, or neurological disorders
• Pregnancy
• Use of drugs affecting neuromuscular function (e.g., anticonvulsants, aminoglycosides)
• History of malignant hyperthermia
• Respiratory disorders, including sleep apnea
• Allergy to anesthetic drugs used in the study

Statin-Using and Non-Using Patients Undergoing Elective Surgery Under General Anesthesia