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we aimed to ascertain the effect of intermittent fasting (IF) vs. high-intensity interval training (HIIT) on the lipid profile and waist circumference (WC) of obese individuals.
Subjects and Methods: This study included 40 obese individuals of both genders aged 35-50 years with an abnormal lipid profile. The patients were allocated at random to either Group A or B, with both groups receiving medical treatment. Group A followed the IF regime, while Group B performed HIIT on the treadmill three times weekly, with an intervention duration of six weeks for both groups. Body mass index (BMI), WC, levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL), high-density lipoprotein (HDL), alongside the Framingham risk score (FRS) were the evaluated variables.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A (IF group) | Experimental | Group A followed the intermittent fasting( IF) regime ,with an intervention duration of six weeks for both groups |
|
| Group B performed High-intensity interval training( HIIT) | Experimental | High-intensity interval training performed on the treadmill three times weekly, with an intervention duration of six weeks for both groups |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| intermittent fasting | Behavioral | Group A participants followed the IF diet for 6 weeks . intermittent fasting , specifically time-restricted feeding (TRF), involves consuming all of one's energy requirements inside an 8-h.The fasting interval was designated as 16 h, and the other 8-h was the eating period . During the 8-h eating window, the patient consumes a well-balanced meal consisting of 55%-65% carbs, 7%-20% protein, and 15%-30% fat . |
| Measure | Description | Time Frame |
|---|---|---|
| lipid profile | A 5 mL fasting venous blood sample was collected following an eight-hour overnight fast, and LDL, HDL, TG, and TC levels were measured. | lipid profile will be measured at baseline, and it will be measured again after six weeks |
| Measure | Description | Time Frame |
|---|---|---|
| waist circumference | Utilizing tape measurements to measure WC.A WC > 40 inches (102 cm) in males and > 35 inches (88 cm) in women indicated an elevated risk for cardiometabolic disorders | waist circumference will be measured at baseline, and it will be measured again after six weeks |
| The Framingham risk score (FRS) |
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Inclusion Criteria:
Inclusion criteria were as follows: (1) A BMI of 30 -40 kg/m2; (2) abnormal lipid profile, with a TC level > 200 mg/dL, an LDL > 100 mg/dL, a TC level > 150 mg/dL, and an HDL < 40 mg/dL; (3) steady vital signs, including blood pressure, respiration rate, and temperature at a baseline level.
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Heba Mousa, lecturer | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Cairo | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37979064 | Result | Nussbaumerova B, Rosolova H. Obesity and Dyslipidemia. Curr Atheroscler Rep. 2023 Dec;25(12):947-955. doi: 10.1007/s11883-023-01167-2. Epub 2023 Nov 18. | |
| 32425570 | Result | Nazari M, Minasian V, Hovsepian S. Effects of Two Types of Moderate- and High-Intensity Interval Training on Serum Salusin-alpha and Salusin-beta Levels and Lipid Profile in Women with Overweight/Obesity. Diabetes Metab Syndr Obes. 2020 Apr 24;13:1385-1390. doi: 10.2147/DMSO.S248476. eCollection 2020. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| low volume high intensity interval training | Behavioral | . Group B engaged in low-volume HIIT exercise (aerobic activity) three times weekly for six weeks. The exercise routine consisted of a 5-min warm-up phase at 70% of MHR, followed by four intervals of 2-min maximum effort cycling sessions (4 × 2 HIIT) compared to a sub-maximal workload at 85%-90% of MHR. The participants engaged in four work bouts, with each bout lasting around 4 min and followed by a 4-min rest period. During the workouts, the participants maintained an HR of 60%-70% of their MHR. This resulted in 8 min of intense physical activity during each training session. Additionally, there was a 5-min cooling down phase at 70% of the MHR. The treatment's intensity was adapted based on the modified Bruce protocol. |
|
It was employed to ascertain the cardiovascular disease risk over ten years. |
| The Framingham risk score (FRS) will be measured at baseline, and it will be measured again after six weeks |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |