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| Name | Class |
|---|---|
| Namik Kemal University School of Medicine, Tekirdag | OTHER |
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This retrospective study evaluates the effects of two different administration methods of the Pericapsular Nerve Group (PENG) Block on postoperative pain control, opioid consumption, and recovery in patients undergoing hip surgery.
All patients in the study received:
The study compares two groups:
Both groups received the same total volume of local anesthetic over 24 hours. All PENG blocks were performed under ultrasound guidance at the end of surgery. This study aims to determine whether intermittent bolus or continuous infusion PENG block administration leads to better pain control, lower opioid consumption, and improved recovery outcomes.
Postoperative pain management after hip surgery remains a critical factor in recovery quality, opioid consumption, and overall patient outcomes. Among regional anesthesia techniques, the PENG Block is increasingly utilized for pain control due to its ability to provide effective analgesia while minimizing systemic opioid use. However, the optimal administration method of PENG block remains unclear.
This retrospective cohort study evaluates the effectiveness of two different PENG block administration techniques in patients undergoing hip surgery:
Total local anesthetic volume over 24 hours was equal in both groups.
Study Objectives:
The primary objective is to compare intermittent bolus vs. continuous infusion PENG block administration in terms of:
Secondary outcomes include:
This study aims to provide evidence on whether intermittent bolus or continuous infusion leads to better pain relief, reduced opioid consumption, and improved recovery in hip surgery patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intermittent Bolus Group | Patients in this group received intermittent bolus administration of the Pericapsular Nerve Group (PENG) Block via a catheter placed under ultrasound guidance at the end of surgery. A researcher manually administered 20 mL of 0.25% bupivacaine every 4 hours over a 24-hour period.
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| Continuous Infusion Group | Patients in this group received continuous infusion of the Pericapsular Nerve Group (PENG) Block via a catheter placed under ultrasound guidance at the end of surgery. A pump delivered 5 mL/hour of 0.25% bupivacaine continuously over a 24-hour period.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intermittent Bolus PENG Block | Procedure | Patients received intermittent bolus administration of the Pericapsular Nerve Group (PENG) Block via a catheter. A researcher manually administered 20 mL of 0.25% bupivacaine every 4 hours over a 24-hour period. |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Pain Scores (VAS) | Postoperative pain levels will be assessed using the Visual Analog Scale (VAS, 0-10) where:
| From 0 hours (postoperatively) to 24 hours postoperatively, assessed at 0, 2, 6, 12, and 24 hours. |
| Measure | Description | Time Frame |
|---|---|---|
| Total Postoperative Opioid Consumption | Total opioid consumption (including PCA tramadol) will be recorded and converted into morphine milligram equivalents (MME) for comparison between groups. | From 0 hours (postoperatively) to 24 hours postoperatively, assessed at 0, 2, 6, 12, and 24 hours. |
| Quality of Recovery (QoR-15 Score) |
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Inclusion Criteria
Participants must meet all of the following criteria to be included in the study:
Participants who meet any of the following criteria will be excluded from the study:
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This study includes adult patients (ages 18-65) who underwent hip surgery at Tekirdağ Namık Kemal University Hospital between November 15, 2023, and November 15, 2024. All patients received Pericapsular Nerve Group (PENG) Block via a catheter for postoperative pain management, along with multimodal analgesia including tramadol PCA, IV paracetamol, and rescue NSAIDs. The study compares two PENG block administration techniques: intermittent bolus versus continuous infusion.
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| Name | Affiliation | Role |
|---|---|---|
| Cavidan Arar, Prof. Dr. | Medical Faculty of Tekirdağ Namık Kemal University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Tekirdağ Namık Kemal University Research Hospital | Tekirdağ | 59000 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36105907 | Background | Huda AU, Ghafoor H. The Use of Pericapsular Nerve Group (PENG) Block in Hip Surgeries Is Associated With a Reduction in Opioid Consumption, Less Motor Block, and Better Patient Satisfaction: A Meta-Analysis. Cureus. 2022 Sep 6;14(9):e28872. doi: 10.7759/cureus.28872. eCollection 2022 Sep. | |
| 36964012 | Background |
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Individual participant data (IPD) will not be shared due to ethical considerations and institutional privacy regulations. Only de-identified, aggregated results will be published in scientific journals and conferences."
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| Continuous Infusion PENG Block | Procedure | Patients received continuous infusion of the Pericapsular Nerve Group (PENG) Block via a catheter. A pump delivered 5 mL/hour of 0.25% bupivacaine continuously over a 24-hour period. |
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The Quality of Recovery-15 (QoR-15) questionnaire will be used to assess the patient's postoperative recovery quality, including physical and emotional well-being. The QoR-15 is a validated tool that measures postoperative recovery across five domains: physical comfort, emotional state, psychological support, physical independence, and pain. Scale Range: 0 to 150 Interpretation: Higher scores indicate better recovery quality. Time Frame: Assessed at 24 hours postoperatively. |
| Assessed at 24 hours postoperatively. |
| Postoperative Nausea and Vomiting (PONV) Incidence | Incidence of postoperative nausea and vomiting (PONV) will be recorded based on medical chart reviews and antiemetic administration (ondansetron IV use). | From 0 hours (postoperatively) to 24 hours postoperatively. |
| Time to First Rescue Analgesia | The time from surgery completion to the first NSAID rescue analgesia administration (ketorolac or dexketoprofen) will be recorded. | From the end of surgery until the first administration of rescue analgesia, assessed up to 24 hours postoperatively. |
| Incidence of Complications | Any adverse events (hematoma, infection, nerve injury, hemodynamic instability, etc.) will be documented from patient records. | From 0 hours (postoperatively) to 24 hours postoperatively. |
| Kukreja P, Uppal V, Kofskey AM, Feinstein J, Northern T, Davis C, Morgan CJ, Kalagara H. Quality of recovery after pericapsular nerve group (PENG) block for primary total hip arthroplasty under spinal anaesthesia: a randomised controlled observer-blinded trial. Br J Anaesth. 2023 Jun;130(6):773-779. doi: 10.1016/j.bja.2023.02.017. Epub 2023 Mar 22. |
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| D000377 | Agnosia |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009422 | Nervous System Diseases |
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