Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The GAMEFILM Registry is a post-market, multi-center, data collection study assessing the presence of CAD in NFL alumni.
The GAMEFILM Registry is a post-market, multi-center, data collection study assessing the prevalence and severity of CAD in NFL alumni. A retired NFL player is defined as any former player who made either a practice squad or an active NFL roster. Approximately 300 participants will be included from approximately 20 sites in the US.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| NFL Alumni | A retired NFL player is defined as any former player who made either a practice squad or an active NFL roster. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Coronary computed tomography angiography | Diagnostic Test | Coronary Computed Tomography Angiography (CCTA) is a non-invasive medical imaging test that uses X-rays to create detailed 3D images of the heart and its blood vessels, specifically the coronary arteries. |
| Measure | Description | Time Frame |
|---|---|---|
| Participants with CAD | The proportion of participants with coronary artery disease demonstrated on coronary computed tomography angiography (CCTA). | 24 hours from the time CCTA was taken |
| Measure | Description | Time Frame |
|---|---|---|
| Participants with physiologically significant CAD | 1. The proportion of participants with physiologically significant CAD (FFRct ≤ 0.80) | 24 hours from the time CCTA was taken |
| Participants with high coronary plaque burden |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
The study population is retired NFL alumni. A retired NFL player is defined as any former player who made either a practice squad or an active NFL roster.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| HeartFlow | Contact | 650-241-1221 | GAMEFILM@heartflow.com |
| Name | Affiliation | Role |
|---|---|---|
| Jeffrey Boone | Boone Heart Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Boone Heart Institute | Recruiting | Greenwood Village | Colorado | 80111 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003324 | Coronary Artery Disease |
| D006331 | Heart Diseases |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D002318 | Cardiovascular Diseases |
| D001161 | Arteriosclerosis |
Not provided
Not provided
Not provided
Not provided
Not provided
2. The proportion of participants with high coronary plaque burden (>75th percentile for age- and sex-matched peers)
| 24 hours from the time CCTA was taken |
| D001157 |
| Arterial Occlusive Diseases |
| D014652 | Vascular Diseases |