Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The goal of this observational study is to determine whether an aquagenic wrinkling procedure (i.e., soaking hands in a water bath for up to 20 minutes) can be used as a screening tool for cystic fibrosis carrier status.
Participants will complete one visit where they will undergo an aquagenic wrinkling procedure to see how their hands respond.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Potential Cystic Fibrosis Carriers | Participants that are identified as potential cystic fibrosis carriers based on aquagenic wrinkling results. |
| |
| Potential Controls | Participants that are identified as potential controls based on aquagenic wrinkling results. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Aquagenic Wrinkling | Procedure | Participants will be asked to remove all jewelry from the hand(s) and wrist(s) that will be undergoing the aquagenic wrinkling procedures. Photographs will be taken of the palmar surface of the hand(s). The participant will submerge the hand(s) undergoing testing in a water bath for one minute. After one minute, they will remove their hand(s), dry them gently with a towel, and photographs will be taken of the palmar surface of the hand(s). The participant will re-submerge their hand(s) in the appropriate conditions for another minute and the process will be repeated 20 times for 20 total minutes submerged in the water. |
| Measure | Description | Time Frame |
|---|---|---|
| Human Observation of Wrinkling | Photos of hands will be scored on a scale of 0 (no wrinkling) to 4 (severe wrinkling) at each minute by human observers. | Up to 20 minutes |
| Machine-Learning Observation of Wrinkling | Photos of hands will be scored by a machine-learning algorithm at each minute. | Up to 20 minutes |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
University students
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Philip M Polgreen, MD | Contact | 319-384-6194 | philip-polgreen@uiowa.edu | |
| Shelby L Francis, PhD | Contact | 319-678-8037 | shelby-francis@uiowa.edu |
| Name | Affiliation | Role |
|---|---|---|
| Philip M Polgreen, MD | University of Iowa | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Iowa | Recruiting | Iowa City | Iowa | 52242 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|