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| ID | Type | Description | Link |
|---|---|---|---|
| R01AG082771-01A1 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute on Aging (NIA) | NIH |
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The investigators will perform a parallel-group multicenter randomized controlled trial of a 1-year pre-enrolled acute hospital care at home intervention vs usual care for people living with dementia. Patients will be randomized only after eligibility determination and after the family caregiver agrees to enroll; people living with dementia will assent when able. Patients will be allocated in a concealed fashion to the control and intervention groups in randomly selected block sizes of 4 or 6 in 4 strata reflecting their functional status (activities of daily living: 0, 1, 2-3, 4-6). Although family and clinicians cannot be blinded, the investigators will blind the data collectors and assessors.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Usual care | Active Comparator | Acute care at a brick-and-mortar hospital. |
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| Acute hospital care at home | Experimental | Home visit for a serious illness conversation. Acute illness evaluation on demand. Acute hospital care at home as needed. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Acute hospital care at home | Other | Home visit for a serious illness conversation. Acute illness evaluation on demand. Acute hospital care at home as needed. |
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| Measure | Description | Time Frame |
|---|---|---|
| Number of days at home | Sum of the number of days spent at home within the 30-days after an acute care episode | Discharge to 30-days post discharge, up to 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| 30-day unplanned readmission or mortality | Percentage of unplanned readmissions or mortality | Discharge to 30-days post discharge, up to 30 days |
| Delirium | Percentage of days experiencing delirium while receiving acute care using the short confusion assessment method. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| David M Levine, MD, MPH, MA | Contact | 617-732-7063 | dmlevine@bwh.harvard.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Brigham and Women's Hospital | Boston | Massachusetts | 02120 | United States |
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| ID | Term |
|---|---|
| D003704 | Dementia |
| ID | Term |
|---|---|
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D019965 | Neurocognitive Disorders |
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Data collectors
| Standard medical treatment | Other | Standard acute and emergency care delivered in a brick-and-mortar hospital setting. |
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| Date of admission to date of discharge, estimated 5 days |
| Health-related quality of life | Absolute change of health-related quality of life over the year through the dementia quality of life survey (DEMQOL), or for patients unable to complete the survey, its proxy version (DEMQOL-Proxy). | From enrollment for the period of one year |
| Physical activity | Percent of time sedentary as measured by patch monitoring system. | Date of admission to date of discharge, estimated 5 days |
| D001523 | Mental Disorders |