Characterization of subjective discomfort/pain in patients with ocular surface dysfunction in association with clinical and laboratory parameters, for a better understanding of the underlying pathogenic mechanisms.

Dry Eye Disease (DED) is a multifactorial chronic disease impairing the ocular surface.

DED can be associated with conditions of inflammation and neurosensory dysfunction.

The aim of this study is to characterize the discomfort/pain in subjects affected by DED with the administration of scales, questionnaires, and analysis of corneal sensitivity by keratoesthesiometry, in association with clinical laboratory parameters.

Inclusion Criteria:

• adult patients with suspected or diagnosed DED

Exclusion Criteria:

• nothing

Participants in the study are patients suffering from ocular disconfort who are referred by their doctors for second/third level diagnostic tests at the University Ophthalmology Department. Patients are adults of both sexes, with eventual concomitant systemic and other ocular pathologies, without any limitation that defines exclusion criteria.