Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The objective is to evaluate the mass balance of [14C]HRS-7535 in healthy adult Chinese subjects.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| [14C]HRS-7535 | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| [14C]HRS-7535 | Drug | [14C]HRS-7535. |
|
| Measure | Description | Time Frame |
|---|---|---|
| The time of maximum observed concentration (Tmax) | 0-120 hours. | |
| The maximum observed concentration (Cmax) | 0-120 hours. | |
| The terminal half-life (t1/2) | 0-120 hours. | |
| The total body clearance for extravascular administration (CL/F) | 0-120 hours. | |
| The total radioactivity ratio for blood | 0-96 hours. | |
| The total radioactivity ratio for plasma | 0-96 hours. |
| Measure | Description | Time Frame |
|---|---|---|
| Adverse events (AEs) | 0-11 days. | |
| Serious adverse events (AEs) | 0-11 days. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The First Affiliated Hospital of Nanjing Medical University | Nanjing | Jiangsu | 210029 | China |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| D015431 | Weight Loss |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| D004700 | Endocrine System Diseases |
| D001836 | Body Weight Changes |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |