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| ID | Type | Description | Link |
|---|---|---|---|
| PID2021-123708OB-I00 | Other Grant/Funding Number | Spanish Ministry of Science and Innovation. Spanish State Research Agency |
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| Name | Class |
|---|---|
| Asociación Parkinson Madrid | OTHER |
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The goal of this observational study is to define digital biomarkers of motor symptoms in Parkinson's disease patients using wearable devices. The main questions it aims to answer is:
Participants have to perform a set of guided exercises related to the MDS-UPDRS guide and daily living tasks, in supervised and unsupervised conditions.
The participants must perform a set of exercises related to the MDS-UPDRS III scale and some free-living activities. These tasks must be performed wearing a smartwatch.
The activities will be done in supervised clinical and unsupervised free-living environments. The participants must perfom a baseline and a final assesment in supervised conditions and a week of free living monitoring.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Parkinson's disease group | The inclusion criterion to this group is a diagnosis of Parkinson's disease based on the UK Brain Bank criteria. | ||
| Healthy control group | The inclusion criterion is participants without movement disorders. |
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| Measure | Description | Time Frame |
|---|---|---|
| Biomarkers for the identification of PD patients | A set of biomarkers will be defined for the identification of PD patients by comparing their data with that of healthy subjects. | 1 year |
| biomarkers for the prediction MDS-UPDRS scores in PD patients | A collection of biomarkers will be calculated to predict MDS-UPDRS scores in PD patients | 1 year |
| Biomarkers in supervised and unsupervised conditions | A comparation between the biomarkers defined in supervised settings versus those defined in free-living environments. | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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For the PD group, an initial and final evaluation will take place at the Asociación Parkinson Madrid. For the control group, the meeting will be at the Escuela Técnica Superior de Ingenieros Industriales at Universidad Politécnica de Madrid (ETSII-UPM).
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidad Politécnica de Madrid | Madrid | Madrid | 28006 | Spain |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Background | Polvorinos-Fernández, C. et al. Evaluating Motor Symptoms in Parkinson's Disease Through Wearable Sensors: A Systematic Review of Digital Biomarkers. Appl. Sci. 2024, 14, 10189. https://doi.org/10.3390/app142210189 | ||
| 38148984 | Background | Sigcha L, Polvorinos-Fernandez C, Costa N, Costa S, Arezes P, Gago M, Lee C, Lopez JM, de Arcas G, Pavon I. Monipar: movement data collection tool to monitor motor symptoms in Parkinson's disease using smartwatches and smartphones. Front Neurol. 2023 Dec 7;14:1326640. doi: 10.3389/fneur.2023.1326640. eCollection 2023. | |
| 40720803 |
| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| Derived |
| Polvorinos-Fernandez C, Sigcha L, Centeno-Cerrato M, de Arcas G, Grande M, Marin M, Parees I, Martinez-Castrillo JC, Pavon I. Evaluation of Free-Living Motor Symptoms in Patients With Parkinson Disease Through Smartwatches: Protocol for Defining Digital Biomarkers. JMIR Res Protoc. 2025 Jul 28;14:e72820. doi: 10.2196/72820. |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |