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| Name | Class |
|---|---|
| University Hospital, Zürich | OTHER |
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Effect of acute exercise testing in pregnant athletes on maternal and fetal heart rate, fetal/maternal bloodflow and cardiotocogramm assessment.
The aim of the study is to evaluate in a preliminary step the validity of fetal heart rate measurement with the "Nemo Healthcare Monitoring System" - a wireless non-invasive CTG device. Furthermore, we will determine the reliability for CTG measurements (intraobserver and interobserver reliability) and for ultrasound (intraobserver reliability). The device is approved for use on pregnant women and is regularly used as a CTG device for monitoring fetal heart rate and contractions during childbirth. If in the preliminary step the heart rate measurements with the "Nemo Fetal Monitoring System" provide valid and fetal heart rate results compared to the standard Doppler ultrasound method and provide a reliable detection of fetal heart rate deceleration the effects of phys-ical activity on fetal heart rate pattern and changes in fetal blood flow, placento-fetal and materno-placental blood supply rate will be investigated in the main part of the study in a larger study population.
It is hypothesized that CTG provides technically a valid and reliable continuous re-cording of fetal heart rate values, since fetal heart rate measurement under physical exertion has previously only been possible by intermittent but not continuous Dop-pler ultrasound. Furthermore, we will evaluate alterations in fetal heart rate pattern and changes in fetal blood flow, placento-fetal and materno-placental blood supply according to the level of exertion.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| exercise testing | Other | incremental cycling test on a bicycle ergometer |
| Measure | Description | Time Frame |
|---|---|---|
| fetal heart rate | The fetal heart rate is continuously monitored via the CTG device during the entire performance test. | through exercise testing, an average of 90 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Umbilical cord artery pulsatility index | (systolic velocity - diastolic velocity) / mean velocity | through exercise testing, an average of 90 minutes |
| Umbilical cord artery resistance index | (systolic velocity - diastolic velocity) / systolic velocity |
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Inclusion Criteria:
Exclusion Criteria:
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pregnant athletes
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nora Wieloch, Dr. med. | Contact | 0041443861111 | nora.wieloch@balgrist.ch | |
| Nina Kimmich, PD Dr. med. | Contact | 0041442551111 | nina.kimmich@usz.ch |
| Name | Affiliation | Role |
|---|---|---|
| Johannes Scherr, Prof. Dr. med. | University Centre for Prevention and Sports Medicine, Department of Orthopaedics, Balgrist University Hospital, University of Zurich, Zurich, Switzerland | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Balgrist University Hospital | Recruiting | Zurich | Canton of Zurich | 8008 | Switzerland |
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| ID | Term |
|---|---|
| D005316 | Fetal Distress |
| ID | Term |
|---|---|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D005080 | Exercise Test |
| ID | Term |
|---|---|
| D006334 | Heart Function Tests |
| D003935 | Diagnostic Techniques, Cardiovascular |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
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| through exercise testing, an average of 90 minutes |
| umbilical cord artery S/D ratio | (S = maximum systolic flow velocity; D = maximum diastolic flow velocity) | through exercise testing, an average of 90 minutes |
| Medial cerebral artery pulsatility index | (systolic velocity - diastolic velocity) / mean velocity | through exercise testing, an average of 90 minutes |
| Medial cerebral artery resistance index | (systolic velocity - diastolic velocity) / systolic velocity | through exercise testing, an average of 90 minutes |
| medial cerebral artery peak systolic velocity | in cm/s | through exercise testing, an average of 90 minutes |
| right and left uterine artery pulsatility index | (systolic velocity - diastolic velocity) / mean velocity | through exercise testing, an average of 90 minutes |
| right and left uterine artery resistance index | (systolic velocity - diastolic velocity) / systolic velocity | through exercise testing, an average of 90 minutes |
| cerebro-placental ratio | pulsatility index of the middle cerebral artery / pulsatility index of the umbilical artery | through exercise testing, an average of 90 minutes |
| pregnancy complications | incidence of pregnancy complications (yes/no); | during pregnancy and up to12 weeks after birth |
| birth complications | incidence of birth complications (yes/no); | On the day the child is born |
| mode of delivery | spontaneous birth vs. vacuum-assisted birth vs. forceps-assisted birth vs planned cesarean section vs. unplanned cesarean section | On the day the child is born |
| APGAR score | APGAR score (1-10) | On the day the child is born |
| gestational age at birth | gestational age at birth (in weeks and days); | On the day the child is born |
| pH value of the umbilical cord artery | pH value of the umbilical cord artery mesured directly after birth | On the day the child is born |
| fetal admission to Neonatal Intensive Care Unit | admission (yes/no) | up to 12 weeks |
| University Hospital Zurich | Recruiting | Zurich | Canton of Zurich | 8091 | Switzerland |
|
| D012129 | Respiratory Function Tests |
| D003948 | Diagnostic Techniques, Respiratory System |
| D016552 | Ergometry |
| D008919 | Investigative Techniques |