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| ID | Type | Description | Link |
|---|---|---|---|
| 1K23HL170836-01A1 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | NIH |
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Women living with HIV have 2-4x higher risk for cardiovascular disease compared to women without HIV, with women living with HIV in the Southern US being particularly at risk. While an increased prevalence of traditional risk factors (e.g., hypertension, diabetes, and obesity) partially explain this risk, evidence suggests that increased exposure to structural and social stressors (e.g., poverty, discrimination, and stigma) among women living with HIV in the South negatively contribute to cardiovascular disease disparities through their impact on stress. The Stress Management and Resiliency Training (SMART) program is an effective, evidence-based intervention proven to improve resiliency to environmental stressors and reduce the physiologic responses to stress which contribute to cardiovascular disease. While the SMART program has demonstrated efficacy in a wide range of populations and settings, it has not been designed for or tested among women living with HIV in the South, where unique cultural and faith-based context may diminish the uptake and value of the intervention to mitigate cardiovascular disease risk. The purpose of this study is to adapt the evidence-based SMART program in consideration of the needs and contexts of women living with HIV in the Southern US and pilot the adapted intervention to establish the feasibility, acceptability, and preliminary impact of the adapted intervention to reduce stress and mitigate cardiovascular disease risk among this population.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Other | Usual Care |
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| Intervention | Other | Adapted Intervention, Previously Established |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Stress Management and Resiliency Training Program | Behavioral | The Stress Management and Resiliency Training Intervention is an evidence-based intervention to reduce physiologic responses to stress that may contribute to cardiovascular disease risk. The intervention is typically delivered over an 8-week period and works to decrease stress responses by improving psychological resiliency to structural and social stressors and decreasing sympathetic nervous system activation. Eliciting the relaxation response through meditation, mindfulness, and autogenic training are core components. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in blood pressure at baseline, week 8, and week 20 | Measure blood pressure at baseline, end of intervention, and at 12-week follow-up | baseline - week 8 - week 20 |
| Change in Center for Epidemiological Studies Depression Scale Score | Higher score indicates more depressive symptoms (0-60 Range) | baseline - week 8 - week 20 |
| Change in Generalized Anxiety Disorder-7 Scale Score | Higher scores indicate greater symptoms of anxiety (0-21 Range) | baseline - week 8 - week 20 |
| Changes in Perceived Stress Scale Scores | Higher scores indicate greater perceived stress (0 - 40 Range) | baseline - week 8 - week 20 |
| Changes in Connor-Davidson Resilience Scale | Higher scores indicate greater resilience (0-100 Range) | baseline - week 8 - week 20 |
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Inclusion Criteria:
Exclusion Criteria:
Cis-gender women for intervention randomization
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jenni Wise, PhD, MSN | Contact | 2059969459 | jmwise@uab.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Alabama at Birmingham | Recruiting | Birmingham | Alabama | 35294 | United States |
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| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
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| Usual Care | Other | Usual social and clinical services provided to patients at the recruiting clinic |
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