Not provided
Not provided
Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 01ZZ2319A-I | Other Grant/Funding Number | Federal Ministry of Education and Research |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| University Medicine Greifswald | OTHER |
| University Medical Center Mainz | OTHER |
| University Hospital, Aachen | OTHER |
| Klinikum Chemnitz gGmbH |
Not provided
Not provided
Not provided
Not provided
The overarching goal of EyeMatics is to promote an interoperable, sustainable infrastructure for the integration and sharing of data from clinical research to improve personalized medicine in ophthalmology. To achieve this, EyeMatics bundles the expertise and preliminary work of the four consortia of the Medical Informatics Initiative (MII) and the ophthalmological centers of excellence in Germany. The perspective and concerns of patients will be strongly incorporated into the project work through close cooperation with patient representatives and the inclusion of patient feedback on quality of life and treatment success.
EyeMatics aims to improve the understanding of the therapeutic success of eye diseases that are usually treated with intravitreal surgical medication (IVOM). To this end, an exemplary analysis platform for "real" clinical data will be provided and a dashboard for data visualization and analysis will be developed as a web application. The dashboard is to be introduced at all participating hospital sites for research purposes.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Medical success | changes in visual acuity during the course of treatment | with every treatment or controll-visit within 12, 24 and 36 months |
| Measure | Description | Time Frame |
|---|---|---|
| Treatment latency period: | latency period within the treatment and monitoring cycle as days between the indication/OCT examination and the implementation of IVOM treatment | from indication to treatment begin (Depending on the treatment regimen, assessed up to 6 months) |
| Treatment and monitoring frequency |
Not provided
Inclusion Criteria:
Not provided
Not provided
Not provided
Patients receiving intravitreal injections at the study centers with signed Broad Consent (Consent of the Medical Informatics Initiative Germany).
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Nicole Eter, Prof. Dr. | Contact | 00492518356004 | eter@uni-muenster.de |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinikum Chemnitz gGmbH | Recruiting | Chemnitz | Saxony | 09116 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39542916 | Result | Holtrup L, Varghese J, Schuster AK, Poschkamp B, Hampf C, Waltemath D, Wahle L, Lipprandt M, Merle DA, Berens P, Kohlbacher O, Kakkassery V, Bartos M, Ziemssen F, Wendt T, Hoffmann K; EyeMatics Study Group; Eter N. [EyeMatics-Multicenter data evaluation of real-world data with interoperable medical informatics]. Ophthalmologie. 2025 Apr;122(4):270-277. doi: 10.1007/s00347-024-02135-0. Epub 2024 Nov 14. German. |
Not provided
Not provided
Not provided
| OTHER |
| Technische Universität Dresden | OTHER |
| University of Leipzig | OTHER |
| University Hospital Tuebingen | OTHER |
| Deutsche Ophthalmologische Gesellschaft e.V. | UNKNOWN |
| Pro Retina Deutschland e.V. | UNKNOWN |
Not provided
Not provided
Not provided
Considered for the injection upload phase and for the first 12, 24 and 36 months of treatment. The number of injections is evaluated at patient level as a quality indicator and for the various treatment regimens, indications and clinical centers. |
| during the procedure |
| Treatment adherence | Non-adherence to treatment is defined as those patients who did not receive any control or therapy without a planned treatment/control gap of 3 months. | during the procedure |
| Treatment persistence | Treatment non-persistence is defined as the number of patients who received no further monitoring or treatment for a period of at least 6 months and did not resume treatment at the time of analysis. | during the procedure |
| Patient-relevant outcomes (PROMs) | intravitreal injection specific PROM-questionnaire, including aspects of visual quality of life, socio-emotional quality of life, therapy and therapy environment, process quality, internal quality management, knowledge of the disease and pain | every 6 months within 12, 24 and 36 months |
| Universitätsklinikum Aachen, AöR | Recruiting | Aachen | 52074 | Germany |
|
| Universitätsmedizin Greifswald | Recruiting | Greifswald | 17475 | Germany |
|
| Universität Leipzig | Recruiting | Leipzig | 04109 | Germany |
|
| Universität Münster | Recruiting | Münster | 48149 | Germany |
|
| Universitätsklinikum Tübingen | Recruiting | Tübingen | 72076 | Germany |
|