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Evaluating the effectiveness of using a single immediate postoperative intramuscular Dexamethasone injection on pain, swelling, trismus and tissue healing in the first seven days.
Methods: A split mouth technique on 16 patients with bilateral similar impacted mandibular third molar were extracted; one side was given 8mg intramuscular injection of dexamethasone (study group) and the other side wasn't given injection (control group) and compare of the two sides were done in the following seven days.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| dexamethasone immediate injection postoperatively | Active Comparator | intramuscular injection of a single dose 8mg dexamethasone immediate postoperatively after removal of impacted mandibular third molar |
|
| no intervention | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dexamethasone | Drug | single 8mg post-operative intramuscular injection |
|
| Measure | Description | Time Frame |
|---|---|---|
| post operative pain changes | measurement of change in pain on visual scale analog from 10 to 1 , 10 mean the worst pain and 1 is least pain | each participant was seen at 1st, 3rd and 7th post-operative days |
| Change in post operative swelling | The swelling was measured between two points marked on skin in millimeters using ruler | each participant was seen at 1st, 3rd and 7th post-operative days |
| Post operative Change in mouth opening | The distance between upper and lower incisors was measured in millimeters using ruler | each participant was seen at 1st, 3rd and 7th post-operative days |
| Measure | Description | Time Frame |
|---|---|---|
| Tissue healing | Healing of extraction site was assessed by using Landry, Turnbull and Howley index | Healing was assessed on the 7th postoperative day |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Baghdad | Baghdad | Iraq |
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Each patient resembles the study group in which the patient is injected intramuscularly by a single dose 8mg dexamethasone immediate postoperatively after removal of impacted mandibular third molar on one side and control group on which the impacted mandibular third molar on the other side is removed without usage of 8mg dexamethasone.
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| ID | Term |
|---|---|
| D003907 | Dexamethasone |
| ID | Term |
|---|---|
| D011246 | Pregnadienetriols |
| D011245 | Pregnadienes |
| D011278 | Pregnanes |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
| D013259 | Steroids, Fluorinated |
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