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This is a single-centre, observational prospective study of cancer patients in remission administering FL Nourish capsules (FLNC), a proprietary Chinese Medicine herbal supplement, for the treatment of symptoms associated with qi deficiency and blood stasis syndrome.
Consultation data will be analysed from up to 24 cancer patients in remission receiving routine treatment at Singapore Thong Chai Medical Institution. Each participant will visit the institution in accordance with the protocol which includes up to 9 months of FL Nourish capsule (FLNC) use and up to 8 consultation visits. Participants will be evaluated based on consultation data, questionnaire data, routine blood test data and self-reporting of adverse events or severe adverse events. As this is a non-interventional observational study, all participants would have received FLNC prescriptions according to routine diagnostic and prescribing standards, and there were no additional visits required aside from routine follow up consultations.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| FLNC Group |
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| Measure | Description | Time Frame |
|---|---|---|
| Pre-post values of EORTC QLQ-C30 questionnaire test scores | 0 is equivalent to a low QoL/functioning/symptom score and 100 indicates the best posssible QoL/functioning/symptom score. | From enrollment to the end of treatment at 10 months |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of unanticipated adverse events or severe adverse events: estimated to be <= 10% | From enrollment to the end of treatment at 10 months | |
| Pre-post values of Alanine aminotransferase (ALT) | From enrollment to the end of treatment at 10 months |
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Inclusion Criteria:
Exclusion Criteria:
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Clinical stable, post-treatment cancer patients.
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| Name | Affiliation | Role |
|---|---|---|
| Huang Fang Zheng, PhD, BS | Singapore Thong Chai Medical Institution | Study Director |
| Renyuan Shen, MS, BA | Singapore Thong Chai Medical Institution | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Singapore Thong Chai Medical Institution | Singapore | SG | 169874 | Singapore |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39840742 | Background | Chan A, Chan D, Ng DQ, Zheng HF, Tan QM, Tan CJ, Toh JHM, Yap NY, Toh YL, Ke Y, Wang ECA, Lim QPN, Ho HK, Chew L, Tan TJ. HEalth-Related Quality of Life-Intervention in Survivors of Breast and Other Cancers Experiencing Cancer-Related Fatigue and Associated Cognitive Symptoms Using TraditionAL Chinese Medicine: The 'HERBAL' Trial. Integr Cancer Ther. 2025 Jan-Dec;24:15347354251314514. doi: 10.1177/15347354251314514. |
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| ID | Term |
|---|---|
| D009369 | Neoplasms |
| D005221 | Fatigue |
| ID | Term |
|---|---|
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| Pre-post values of Aspartate aminotransferase (AST) | From enrollment to the end of treatment at 10 months |
| Pre-post values of albumin-to-creatinine ratio (ACR) | From enrollment to the end of treatment at 10 months |