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| Name | Class |
|---|---|
| Catholic University of the Sacred Heart | OTHER |
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The goal of this study is to investigate whether the use of artificial intelligence platforms can promote the retrieval of specific positive autobiographical memories.
The decision to focus on the retrieval of positive autobiographical memories was made for ethical reasons and is not tied to any specific research hypothesis. Specifically, the study aims to assess whether artificial intelligence facilitates the sharing of personal experiences and reflection on autobiographical memories related to substance use disorders, taking into account the potential influence of individual characteristics such as recent mood state, and overall memory functioning.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Avatar / Face-to-face | Experimental | SUD patients were investigated using the Autobiographical Memory Test in two conditions: face-to-face and avatar-based interactions. Patients had to recall 6 neutral cue words and 6 substance-related cue words for each condition. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| avatar-based interactions | Device | SUD patients were investigated using the Autobiographical Memory Test in two conditions: face-to-face and avatar-based interactions. Patients had to recall 6 neutral cue words and 6 substance-related cue words for each condition. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Specific Autobiographical Memory Recall | The primary outcome measure is the difference in the number of specific autobiographical memories recalled between the avatar-based interaction condition and the face-to-face condition, as assessed by the Autobiographical Memory Test (AMT). Specificity of recalled memories are scored using standardized criteria. This measure evaluates the effectiveness of avatar-based interventions in changing AM recall in patients with substance use disorder (SUD). | During the intervention sessions for both conditions (avatar-based and face-to-face). This outcome directly reflects the study's objective by quantifying the change of AM recall through avatar-based interventions. |
| Measure | Description | Time Frame |
|---|---|---|
| Latency of Autobiographical Memory Recall | The secondary outcome measure is the comparison of latency times (time taken to recall a memory) between the avatar-based interaction condition and the face-to-face condition, as recorded during the Autobiographical Memory Test (AMT). This measure evaluates whether the use of avatar-based interventions change the speed of autobiographical memory recall in patients with substance use disorder (SUD). |
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Fabio Frisone, PhD | Catholic University of the Sacred Heart | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Le.L.A.T. Lega Lotta Aids E Tossicodipendenza | Messina | 98124 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28756101 | Background | Nandrino JL, Gandolphe MC, El Haj M. Autobiographical memory compromise in individuals with alcohol use disorders: Towards implications for psychotherapy research. Drug Alcohol Depend. 2017 Oct 1;179:61-70. doi: 10.1016/j.drugalcdep.2017.06.027. Epub 2017 Jul 21. | |
| 28556207 | Background | Nandrino JL, Gandolphe MC. Characterization of Self-Defining Memories in Individuals with Severe Alcohol Use Disorders After Mid-Term Abstinence: The Impact of the Emotional Valence of Memories. Alcohol Clin Exp Res. 2017 Aug;41(8):1484-1491. doi: 10.1111/acer.13424. Epub 2017 Jun 14. |
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We plan to share the Individual Participant Data (IPD) starting from January 25, 2025. The data will be made available for research purposes to qualified researchers who submit a formal request and have an approved data-sharing agreement. Access will be contingent upon ensuring that proper data protection and confidentiality measures are followed, in compliance with ethical guidelines and applicable data protection laws. The data will not be shared for commercial purposes without further approval. The IPD will be made available for 5 years from the date of release.
The data will become available starting from January 25, 2025. The data will remain available for 5 years from the date of release. Access to the data will be granted to qualified researchers upon request and following approval of a data-sharing agreement to ensure proper use and confidentiality.
Access to the data will be granted to qualified researchers who have a legitimate research purpose. Researchers must submit a formal request detailing the proposed study, its objectives, and the intended use of the data. Access will be contingent upon approval of a data-sharing agreement, which will outline the terms and conditions of use, including confidentiality and data security measures. The data will be provided only for research purposes and cannot be used for commercial purposes without further agreement.
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| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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within-subject design
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| During the intervention sessions for both conditions (avatar-based and face-to-face). |
| Pleasantness of Autobiographical Memories Recalled | The secondary outcome measure is the comparison of pleasantness ratings of autobiographical memories recalled between the avatar-based interaction condition and the face-to-face condition. Pleasantness is assessed during the Autobiographical Memory Test (AMT). This measure evaluates whether avatar-based interventions change the emotional valence of the memories retrieved by patients with substance use disorder (SUD). | During the intervention sessions for both conditions (avatar-based and face-to-face). |
| Change in Age Memory Recall | The secondary outcome measure is the change in age memory recall, defined as the participants' ability to identify the age at which autobiographical memories occurred, comparing the avatar-based interaction condition to the face-to-face condition. Age memory is assessed during the Autobiographical Memory Test (AMT) for each recalled memory. This measure evaluates whether avatar-based interventions change temporal specificity in autobiographical memory recall among patients with substance use disorder (SUD). | During the intervention sessions for both conditions (avatar-based and face-to-face). |
| 36950753 | Background | De Groote C, Cottencin O, Tison P, Triquet C, Nandrino JL. Autobiographical memories cued by self-statements in patients with alcohol use disorder: linking self-conceptions to past events. Memory. 2023 May;31(5):732-746. doi: 10.1080/09658211.2023.2191899. Epub 2023 Mar 22. |
| 26990362 | Background | Nandrino JL, El Haj M, Torre J, Naye D, Douchet H, Danel T, Cottencin O. Autobiographical Memory Deficits in Alcohol-Dependent Patients with Short- and Long-Term Abstinence. Alcohol Clin Exp Res. 2016 Apr;40(4):865-73. doi: 10.1111/acer.13001. Epub 2016 Mar 17. |
| 34401366 | Background | Fernandez-Alvarez J, Colombo D, Suso-Ribera C, Chirico A, Serino S, Di Lernia D, Palacios AG, Riva G, Botella C. Using virtual reality to target positive autobiographical memory in individuals with moderate-to-moderately severe depressive symptoms: A single case experimental design. Internet Interv. 2021 May 27;25:100407. doi: 10.1016/j.invent.2021.100407. eCollection 2021 Sep. |
| 39463396 | Background | Lenormand D, Mentec I, Gaston-Bellegarde A, Orriols E, Piolino P. Decoding episodic autobiographical memory in naturalistic virtual reality. Sci Rep. 2024 Oct 27;14(1):25639. doi: 10.1038/s41598-024-76944-3. |
| 37972046 | Background | Frisone F, Brizzi G, Riva G. VR-MEM: Harnessing Virtual Reality for Autobiographical Memory Enhancement in High School Settings. Cyberpsychol Behav Soc Netw. 2024 Jan;27(1):91-93. doi: 10.1089/cyber.2023.29300.ceu. Epub 2023 Nov 16. No abstract available. |
| 38717129 | Background | Frisone F, Calabro G, Rossi C, Riva G. MEM-AV: A VR-Based Approach to Improve Autobiographical Memory Retrieval in Addiction. Cyberpsychol Behav Soc Netw. 2024 May;27(5):353-355. doi: 10.1089/cyber.2024.42624. Epub 2024 May 8. No abstract available. |
| 25307577 | Background | Pitel AL, Eustache F, Beaunieux H. Component processes of memory in alcoholism: pattern of compromise and neural substrates. Handb Clin Neurol. 2014;125:211-25. doi: 10.1016/B978-0-444-62619-6.00013-6. |
| 10789197 | Background | Conway MA, Pleydell-Pearce CW. The construction of autobiographical memories in the self-memory system. Psychol Rev. 2000 Apr;107(2):261-88. doi: 10.1037/0033-295x.107.2.261. |