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| ID | Type | Description | Link |
|---|---|---|---|
| R01MH133515 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Institute of Mental Health (NIMH) | NIH |
| OCHIN, Inc. | OTHER |
| Oregon Health and Science University | OTHER |
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Scale-up of HIV preexposure prophylaxis (PrEP) is a key strategy of the U.S. initiative to end the HIV epidemic, but healthcare providers lack tools to support PrEP discussions and prescribing for patients likely to benefit. This research will evaluate whether integrating automated tools into electronic health records to help providers efficiently and equitably identify potential candidates for PrEP, discuss PrEP, and prescribe PrEP can improve PrEP initiation and persistence in safety-net community health centers. It will achieve this by conducting a stepped-wedge trial of a decision support tool with an embedded HIV prediction model to identify patients likely to benefit from PrEP. The intervention will be delivered to healthcare providers in 16 community health centers within the national OCHIN network.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard of Care | No Intervention | Data will be extracted from EHRs of control clinics as a comparison, and those clinics will not actively participate in study activities | |
| Predictive analytics and clinical decision support | Active Comparator | Providers in enrolled intervention clinics will receive point-of-care notifications via the EHR-embedded decision support tool about patients who are at increased predicted HIV risk and therefore likely to benefit from PrEP |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Predictive Analytics and Clinical Decision Support | Other | The intervention will include automated EHR notifications to clinicians at 16 OCHIN community health centers about patients who are likely to benefit from PrEP. These patients will be identified by an HIV prediction model that was developed and validated during the pilot phase of this study using historical OCHIN EHR data. For patients above a preselected threshold of predicted HIV risk, clinicians will be notified at the point of care that the patient may benefit from PrEP and will be provided with EHR-based tools to support discussions and prescribing. The intervention will also include coaching on PrEP and the decision support tool, as well as project team support during the trial period. |
| Measure | Description | Time Frame |
|---|---|---|
| PrEP initation | Proportion of patients above the prediction model risk threshold without a recently active PrEP prescription (within the prior 6 months) or prior HIV diagnosis who are prescribed PrEP during the study period. | 30 months |
| Measure | Description | Time Frame |
|---|---|---|
| PrEP persistence | Proportion of patients prescribed PrEP who persist on PrEP for 6 and 12 months, as measured by prescription refills ordered. | 30 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bay Area Community Health Liberty Clinic | Fremont | California | 94538 | United States | ||
| Lifelong East Oakland Health Center |
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|
| Oakland |
| California |
| 94605 |
| United States |
| TrueCare Oceanside Family Medicine | Oceanside | California | 92054 | United States |
| DAP Legacy | Palm Springs | California | 92262 | United States |
| One Community Health Midtown Campus | Sacramento | California | 95811 | United States |
| Southwest Community Health Center 968 Fairfield Avenue | Bridgeport | Connecticut | 06605 | United States |
| Mercy Care Decatur Street | Atlanta | Georgia | 30312 | United States |
| Siouxland Community Health Center Sioux City | Sioux City | Iowa | 51105 | United States |
| Lynn Community Health Center 269 Union | Lynn | Massachusetts | 01901 | United States |
| Mattapan Community Health Center Blue Hill | Mattapan | Massachusetts | 02126 | United States |
| Neighborhood Family Practice Ridge Community Health Center | Cleveland | Ohio | 44102 | United States |
| Signature Health Painesville | Painesville | Ohio | 44077 | United States |
| Variety Care Sequoyah | Oklahoma City | Oklahoma | 73112 | United States |
| Prism Belmont | Portland | Oregon | 97214 | United States |
| Bee Busy Wellness Center Bray Oaks | Houston | Texas | 77031 | United States |
| Seattle Roots Community Health Carolyn Downs Community Clinic | Seattle | Washington | 98122 | United States |