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| ID | Type | Description | Link |
|---|---|---|---|
| 2024-0089-004 | Other Grant/Funding Number | Hong Kong Jockey Club Charities Trust |
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The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10). However, retrospective measurements like the CIDI-5 are susceptible to recall bias, especially for the lifetime experience, which can hinder the reporting accuracy with mental disorders.
To mitigate this issue, the life history calendar (LHC) was introduced as an aid to assist respondents in recalling the timing of life events, enhancing the ability of the CIDI-5 to measure the lifetime prevalence of mental disorders. The LHC is a grid structure with columns representing time units and rows representing life domains under study.
In a study conducted in Nepal, combining the CIDI-5 with the LHC resulted in a significant increase in the detection of mental disorders compared to using the CIDI-5 alone. This approach did not lead to an increase in false positives after clinical validation.
This experiment aims to adapt a Hong Kong version of the LHC based on the Nepalese model and evaluate the effectiveness of the LHC-assisted CIDI-5 (LHC-CIDI-5) compared to the CIDI-5 alone in assessing mental disorders.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CIDI-5 | For the CIDI-5 group, respondents will directly partake in the CIDI-5 interview without responding to any inquiries regarding their life history. |
| |
| LHC-CIDI-5 | For the LHC-CIDI-5 group, respondents, before initiating the CIDI-5, will begin with LHC, completing a calendar by answering questions about important personal experiences since birth until the interview year. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CIDI-5 | Diagnostic Test | The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12 months, and lifetime) based on the diagnostic criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders 5th edition (DSM-5) and International Classification of Diseases 10th edition (ICD-10) . Trained interviewers will administrate selected modules from the Hong Kong version of the CIDI-5 in a computer-assisted personal interview to measure the outcomes. |
| Measure | Description | Time Frame |
|---|---|---|
| Depression | The main outcomes in this module are the lifetime prevalence of Major Depressive Episode (MDE) and Major Depressive Disorder (MDD) | Immediately following intervention or recruitment |
| Persistent Depression | The main outcome in this module is the lifetime prevalence of Persistent Depressive Disorder (PDD) | Immediately following intervention or recruitment |
| Self Harm | The main outcomes in this module are the lifetime prevalence of Suicidal Ideation, Suicidal Plan, Suicidal Attempt, Suicidal Gesture, and Nonsuicidal Self-Injury. | Immediately following intervention or recruitment |
| High Mood | The main outcomes in this module are the lifetime prevalence of Manic Episode, Hypomanic, Bipolar I Disorder, Bipolar Sub Disorder, and Bipolar II Disorder | Immediately following intervention or recruitment |
| Worry and Anxiety | The main outcome in this module is the lifetime prevalence of Generalized Anxiety Disorder (GAD) | Immediately following intervention or recruitment |
| Anger Attacks | The main outcome in this module is the lifetime prevalence of Intermittent Explosive Disorder (IED) | Immediately following intervention or recruitment |
| Panic Attacks | The main outcomes in this module are the lifetime prevalence of Panic Attack and Panic Disorder. |
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Inclusion Criteria:
Exclusion Criteria:
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This study is a sub-study of the District Health Profile (DHP), which is a district-level representative descriptive cross-sectional study. In DHP, 1% of households in selected Hong Kong districts will be randomly selected from the Census and Statistics Department's list of quarters, with stratification based on districts and housing types; all persons aged 18 and above in the recruited households will be included and surveyed. For participants who consent to join the DHP study, a sub-sample of 2,500 participants aged 25 or above will be randomly selected and assigned to two groups through a random process. All 2,500 individuals will complete the survey for the DHP study, including the CIDI-5 section. When administering the CIDI-5, one group of 1,250 individuals will be interviewed using only the CIDI-5, while the other group of 1,250 individuals will be interviewed with LHC first, followed by the CIDI-5.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yoona Kim, PhD | Contact | 852+39179109 | yoonak@hku.hk | |
| Rusi Long, MHS | Contact | 852+39102308 | rlong36@hku.hk |
| Name | Affiliation | Role |
|---|---|---|
| Michael Y. Ni, MD | The University of Hong Kong | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Hong Kong | Recruiting | Hong Kong | Hong Kong |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 36654500 | Background | Amro I, Ali A, Hassan MHMO, Al Shawwaf M, Alhassan A, Al Bahari D, El Fakki H, Hijawi Z, Aly S, Amin A, Mohammed R, Nofal M, Abdelkader M, Salman S, Currie J, Alabdulla M, Sampson NA, First M, Kessler RC, Woodruff PW, Khaled SM. Design and field procedures for the clinical reappraisal of the Composite International Diagnostic Interview version 3.3 in Qatar's national mental health study. Int J Methods Psychiatr Res. 2023 Sep;32(3):e1958. doi: 10.1002/mpr.1958. Epub 2023 Jan 18. | |
| 30854987 |
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| LHC-CIDI-5 | Diagnostic Test | The interviewer will start by asking the respondent's age and significant personal experiences, which is expected to take 15 minutes. Remembering and recording the experiences provide cognitive engagement and information which can further serve as memory cues for respondents in the following screening of CIDI-5. Subsequently, the respondents will proceed to the screening section for CIDI-5 and will refer to the completed calendar from the LHC section when they are asked to report lifetime experience or age-of-onset for mental disorders. Trained interviewers will conduct all interviews in a computer-assisted personal interview. To validate the diagnoses in the LHC-CIDI-5 group, clinical re-interviews for MDD, GAD, and PTSD will be conducted by a trained mental health professional with previous experience using DSM-5. |
|
| Immediately following intervention or recruitment |
| Obsessions and Compulsions | The main outcome in this module is the lifetime prevalence of Obsessive-Compulsive Disorder (OCD) | Immediately following intervention or recruitment |
| Stressful Experiences | The main outcomes in this module are the lifetime prevalence of Posttraumatic Stress Disorder (PTSD), PCL-SC PTSD, and PCL-5 PTSD. | Immediately following intervention or recruitment |
| Tobacco, Alcohol, and Drugs | The main outcomes in this module are the lifetime prevalence of Alcohol Use Disorder (AUD) and Substance Use Disorder (SUD) | Immediately following intervention or recruitment |
| Background |
| Axinn WG, Chardoul S, Gatny H, Ghimire DJ, Smoller JW, Zhang Y, Scott KM. Using life history calendars to improve measurement of lifetime experience with mental disorders. Psychol Med. 2020 Feb;50(3):515-522. doi: 10.1017/S0033291719000394. Epub 2019 Mar 11. |
| ID | Term |
|---|---|
| D003865 | Depressive Disorder, Major |
| D059020 | Suicidal Ideation |
| D016728 | Self-Injurious Behavior |
| D000087122 | Mania |
| D001714 | Bipolar Disorder |
| D000098647 | Generalized Anxiety Disorder |
| D007174 | Disruptive, Impulse Control, and Conduct Disorders |
| D016584 | Panic Disorder |
| D009771 | Obsessive-Compulsive Disorder |
| D013313 | Stress Disorders, Post-Traumatic |
| D000437 | Alcoholism |
| D019966 | Substance-Related Disorders |
| D001523 | Mental Disorders |
| ID | Term |
|---|---|
| D003866 | Depressive Disorder |
| D019964 | Mood Disorders |
| D013405 | Suicide |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000068105 | Bipolar and Related Disorders |
| D001008 | Anxiety Disorders |
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D019973 | Alcohol-Related Disorders |
| D064419 | Chemically-Induced Disorders |
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