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Stroke is a known risk factor for the development of osteoporosis, leading to an increased risk of falls and fractures. Several international studies have associated stroke with hip fractures, showing an odds ratio ranging between 1.5 and 4. The literature frequently indicates a lack of management for bone metabolism in patients following cerebrovascular events. This study aims to evaluate the incidence of osteoporosis and fragility fractures in patients with chronic stroke. A secondary aim is to assess whether patients have been adequately screened for bone metabolism following a cerebrovascular event. This study is designed as a prospective observational study. Patients aged over 65 years with chronic stroke are assessed at the U.O.C. of "Functional Recovery and Rehabilitation" at A.O.U.P. "P. Giaccone," Palermo. During the assessment, clinical and demographic data are collected, including details of the cerebrovascular event (location, hemorrhagic/ischemic, date), pre-event and post-event disability/autonomy (Rankin scale), presence of fractures (location and date) in the patient's medical history (pre and post-event), femoral and lumbar DEXA for osteoporosis evaluation, and DeFRA for assessing the 10-year risk of fragility fractures.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Chronic Stroke Patients Aged 65 and Above | This group consists of patients aged 65 years and older who have experienced a chronic stroke. These patients are assessed for the incidence of osteoporosis and fragility fractures, and are evaluated for bone metabolism management following the cerebrovascular event. The study aims to determine the prevalence of osteoporosis and fractures, as well as the effectiveness of screening for bone metabolism disorders in this specific population. |
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| Measure | Description | Time Frame |
|---|---|---|
| Evaluating the Incidence of Osteoporosis and Fragility Fractures in Chronic Stroke Patients | The primary objective of this study is to evaluate the incidence of osteoporosis and fragility fractures in patients with chronic stroke. | From enrollment to the end of treatment at 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Proper screening for bone metabolism in patients after cerebrovascular event | Number of patients who were properly screened for bone metabolism after the cerebrovascular event. | From enrollment to the end of treatment at 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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Participants will be selected from patients aged 65 and older who have experienced a chronic stroke and are receiving treatment at the Neurology and Rehabilitation Departments of hospitals in Palermo, Italy. The population includes both male and female patients who meet the inclusion criteria and are willing to provide informed consent. The study aims to evaluate the incidence of osteoporosis and fragility fractures in this specific population and to assess their bone metabolism management post-cerebrovascular event.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| A.O.U.P. P. Giaccone, Palermo, Italia 90127 | Palermo | Italia | 90127 | Italy |
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| ID | Term |
|---|---|
| D010024 | Osteoporosis |
| D006620 | Hip Fractures |
| ID | Term |
|---|---|
| D001851 | Bone Diseases, Metabolic |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D008659 | Metabolic Diseases |
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| D009750 |
| Nutritional and Metabolic Diseases |
| D005264 | Femoral Fractures |
| D050723 | Fractures, Bone |
| D014947 | Wounds and Injuries |
| D025981 | Hip Injuries |
| D007869 | Leg Injuries |