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Intracerebral non-traumatic intraparenchymal hemorrhages (ICH) account for 15 to 20% of strokes. One third of the patients dies within the month following ICH, and survivors often experience residual disability with a high risk of recurrent ICH, other serious vascular events, and neurological complications such as epilepsy and dementia. Encouraging but preliminary data suggest a favorable trend in terms of survival rates in recent years. This is partly due to improved management of patients with ICH, which must be early (the concept of "time is brain") and carried out by expert personnel (medical and paramedical) in specialized units.
The main objectives of the study are:
The project consists of 2 parts:
Each patient will benefit from management according to a protocol which will include:
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| Measure | Description | Time Frame |
|---|---|---|
| mortality and disability | Primary Outcome Measure Title: Modified Rankin Scale (mRS) Scores to Assess Disability and Mortality Description: The study will evaluate functional outcomes, disability, and mortality in patients with non-traumatic intracerebral hemorrhage. Functional outcomes will be measured using the modified Rankin Scale (mRS), which evaluates the degree of disability or dependence in daily activities. The mRS scores range from 0 (no symptoms) to 6 (death). Data will be summarized as the proportion of participants in each mRS category at 6 months and 2 years. Mortality will be assessed as the percentage of participants with an mRS score of 6. | 6 months, 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| Neuropsychiatric patient profile among the survivors | Cognitive and behavioral outcomes will be measured using a battery of neuropsychiatric tests, including assessments for memory, executive function, attention, and mood disorders (e.g., depression and anxiety). Data will be reported as mean test scores for each domain | 6 months, 2 years |
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Inclusion Criteria:
Exclusion criteria :
- Patient who has given their opposition to the collection of their data
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Adult population with acute ICH
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Marco PASI, MD, PHD | Contact | +33 0247478024 | M.PASI@chu-tours.fr |
| Name | Affiliation | Role |
|---|---|---|
| Marco PASI, MD, PHD | neurovascular unit, neurology department, CHRU Tours | Principal Investigator |
| Grégoire Boulouis, MD, PHD | interventionnal neuroradiology unit, neuroradiology department, CHRU Tours | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital of Angers | Recruiting | Angers | 49100 | France |
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| ID | Term |
|---|---|
| D002543 | Cerebral Hemorrhage |
| ID | Term |
|---|---|
| D020300 | Intracranial Hemorrhages |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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routine blood samples
| University Hospital of Poitiers | Recruiting | Poitiers | 86000 | France |
|
| University Hospital Center of Tours | Recruiting | Tours | 37044 | France |
|
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006470 | Hemorrhage |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |