Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep

The Impact of Nasal Versus Oral Breathing on Measures of Drug-Induced Sleep Endoscopy

This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sleep Endoscopy) is representative of natural sleep.

As part of standard of care, a drug-induced sleep endoscopy will be done, where route of breathing will be determined as a percentage of total breaths (during baseline, lateral sleep and maneuver). As part of the research procedure, an in-laboratory Polysomnogram will be conducted as study procedure including a oronasal pressure signal cannula to assess route of breathing.

Inclusion Criteria:

• • Adults (≥ 18yrs) that underwent clinical evaluation at the CPAP Alternatives Clinic at Penn Otorhinolaryngology.

  • Must have at least mild OSA (AHI>5)

Exclusion Criteria:

• • Sleep study with an AHI<5, >25% of total events being central or mixed events, or inability to achieve adequate drug-induced sleep.

  • Upper Respiratory Illness at the time of the DISE.