Lactose Intolerance in Infants With Gastrointestinal Disturbances

Lactose Intolerance in Infants With Gastrointestinal Disturbances

This study enrolled thirty infants who presented by GIT symptoms and their CoMiSS was ≥ 12. The patients were assessed upon presentation, after 2 weeks of receiving lactose free diet regimen and 2 weeks after rechallenging them with lactose. Assessments of infants included anthropometric measurements, CoMiSS estimation, Neonatal/Infant Pain Scale (NIPS) and pediatric quality of life assessment (Peds QL). The study aims to detect the frequency of infants with LI with positive Cow's Milk-related Symptom Score (CoMiSS) (which could lead to misdiagnosis as CMPA) and validate of this score to be used as a screening tool for LI in infants.

Inclusion Criteria:

• Artificially fed infants.
• Presented with GIT symptoms such as vomiting, diarrhea, abdominal pain, discomfort and distention.
• Cow's Milk-related Symptom Score (CoMiSS) of 12 or higher.

Exclusion Criteria:

• Infants with positive family history of Cow's milk protein allergy CMPA.
• Any allergic diseases.
• History of anaphylaxis.
• Atopic dermatitis, swelling of lips or eyelids, urticaria or wheezy chest.