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| ID | Type | Description | Link |
|---|---|---|---|
| R.24.12.2966 | Registry Identifier | Mansoura University Faculty of Medicine IRB |
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This study aims to evaluate the efficacy and safety of ultrasound-guided needle knife dissection in treating Dupuytren's contracture. The procedure is designed to improve hund function and minimize complications associated with the conventional surgical methods.
Dupuytren's contracture is a disease mainly characterized by the progressive fibrosis of the palmar fascia with subsequent hand deformity and dysfunction. The current study seeks to explore, through this minimally invasive technique, ultrasound-guided needle knife dissection regarding ROM and patient satisfaction. The procedure will be carried out under ultrasound guidance to ensure safety and completeness with the accuracy of precise dissection. Primary outcome measures will concern hand mobility, and secondary measures will evaluate patient self-reported satisfaction and any complications for the 6-month follow-up period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Group: Ultrasound-Guided Needle Knife Dissection | Experimental | Participants in this group will undergo ultrasound-guided needle knife dissection for the treatment of Dupuytren's Contracture. Local anesthesia using 3-5ml of 1% lidocaine 0.25% bupivacaine is administered for patient comfort. This procedure is designed to improve hand function with minimal complications. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ultrasound guided needle knife dissection | Procedure | This procedure involves a minimally invasive dissection of the fibrous cords in Dupuytren's Contracture using a needle knife guided by ultrasound imaging. Local anesthesia using 3-5 ml of 1% Lidocaine and 0.25% bupivacaine is administered for patient comfort. The technique aims to improve precision, minimize complications and reduce recurrence. Device: Sonosite M-Turbo Ultrasound Machine with Linear Probe HFL38x (6-13 MHz) is used for real-time imaging during the procedure. |
| Measure | Description | Time Frame |
|---|---|---|
| Improvement in hand Function | Functional Improvement: - Evaluated using the QuickDASH score (0-100 scale). | 6 months |
| Improvement in hand mobility | Range of Motion (ROM): - Measurment of joint mobility in degrees at MCP and PIP joints by goniometer. | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Patient Satisfaction | Evaluation of patient-reported satisfaction using a standardized questionnaire. | 6 months |
| Rate of procedure-related complications | Monitoring and documentation of procedure-related complications, including infection, nerve injury, and other adverse events. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mohamed Maher Elashmawy, MD, PHD. | Contact | +201004303100 | mohamedmaherismail@mans.edu.eg |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Mansoura University Hospital | Recruiting | Al Mansurah | Dakahlia Governorate | 35516 | Egypt |
The individual participant data (IPD) will not be shared to ensure participant confidentiality and comply with ethical and institutional regulations. The collected data will only be used for the purposes of this study and will not be disclosed to external parties
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| ID | Term |
|---|---|
| D004387 | Dupuytren Contracture |
| ID | Term |
|---|---|
| D005350 | Fibroma |
| D018218 | Neoplasms, Fibrous Tissue |
| D009372 | Neoplasms, Connective Tissue |
| D018204 | Neoplasms, Connective and Soft Tissue |
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All participants will undergo ultrasound-guided needle knife dissection for Dupuytren's Contracture treatment.
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| 6 months |
| D009370 | Neoplasms by Histologic Type |
| D009369 | Neoplasms |
| D003286 | Contracture |
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |