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The objective of this study is to evaluate, using MRI, the microstructural consequences and the onset of any cognitive impairment in female professional soccer players at the end of their career, who have experienced repeated minor head injuries. Over the long term, these head injuries could lead to morphological lesions and have an impact on female soccer players' cognitive skills.
The main evaluation criterion corresponds to the modifications found on MRI in the female professional soccer player group (diffusion tensor, cerebral perfusion, fMRI, cerebral volumetry and cortical thickness, spectroscopy, susceptibility imaging).
This is an exposure/nonexposure study assessing the onset of MRI abnormalities (diffusion tensor, cerebral perfusion, fMRI, volumetry and cortical thickness, spectroscopy, susceptibility imaging) in female professional soccer players exposed to repeated mild head injuries, who are either at the end of their career or retired for approximately 10 years, compared to high-level athletes not exposed to head injuries.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Female professional Soccer players | Experimental | Diagnostic Test: MRI The following sequences of the MRI will be acquired during the inclusion visit:
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| Female athletes not exposed to head injuries. | Active Comparator | Diagnostic Test: MRI The following sequences of the MRI will be acquired during the inclusion visit:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cerebral MRI | Other | Cerebral MRI |
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| Measure | Description | Time Frame |
|---|---|---|
| Cerebral MRI Microstructural abnormalities | Abnormalities on MRI in professional soccer players exposed to repeated mild head injuries, potentially related to chronic traumatic encephalopathy, compared to high-level athletes who are not exposed to head injuries. This is a study assessing the relation between exposure to mild head injuries during soccer play in professional players and the onset of MRI and neuropsychological abnormalities. The main evaluation criterion corresponds to the quantitative MRI modifications (professional soccer player group compared with control group). | Day 1 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Stéphane KREMER, MD | Contact | 03 88 12 78 48 | 0033 | stephane.kremer@chru-strasbourg.fr |
| Name | Affiliation | Role |
|---|---|---|
| Stéphane KREMER, MD | HOPITAUX UNIVERSITAIRES DE STRASBOURG | Principal Investigator |
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| ID | Term |
|---|---|
| D000070627 | Chronic Traumatic Encephalopathy |
| ID | Term |
|---|---|
| D000070642 | Brain Injuries, Traumatic |
| D001930 | Brain Injuries |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 | Nervous System Diseases |
| D020208 | Brain Injury, Chronic |
| D019636 | Neurodegenerative Diseases |
| D006259 | Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D001925 | Brain Damage, Chronic |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014947 | Wounds and Injuries |