Cementation of indirect restoration is a determinant of the success or failure of the fabricated restoration and consequentially the entire tooth. While there are numerous commercially available resin cements in the dental market, not all have been sufficiently assessed with significant follow up periods to clinically determine their success or failure. As such, this research will be conducted to elucidate if there is a viability to the cementation of indirect hybrid ceramic blocks over endodontically treated teeth using bioactive self-adhesive resin cement and determining whether it provides a clinical advantage and improved restoration serviceability in the oral cavity.

Inclusion Criteria:

• Patient Related Criteria:
• Adult patients (age: 21-50 years) of both genders.
• Able to tolerate necessary restorative procedures.
• Willing to sign the informed consent.
• Accepts the follow-up period.

Tooth Related Criteria:

• Endodontically treated first and second permanent molars.
• Access cavities with one missing proximal wall i.e. Occluso-mesial/distal cavities
• Patients with proper oral hygiene

Exclusion Criteria:

• Endodontically treated anterior, premolar and third molar teeth
• Badly broken-down teeth
• Hopelessly carious/destructed teeth necessitating extraction
• Mobile teeth, indicating periodontal disease or trauma.
• External or internal resorption.
• Cervical carious lesions
• Medically compromised patients
• Patients with known allergies to Latex and/or resinous material