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| Name | Class |
|---|---|
| Instituto Dante Pazzanese de Cardiologia | OTHER |
| Irmandade da Santa Casa de Misericordia de Sao Paulo | OTHER |
| Instituto do Coração da Universidade de São Paulo, Brazil | UNKNOWN |
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Cardiovascular diseases continue to be the leading cause of death worldwide. Among them, coronary artery disease has the greatest impact, being characterized as one of the main causes of death in Brazil over the last decade. One of the well-established treatments is coronary artery bypass grafting, which is the most performed among cardiac surgeries and, in our scenario, is primarily funded by the Unified Health System (SUS). The information obtained from the Paulista Registry of Cardiovascular Surgeries (REPLICCAR), in partnership with FAPESP, has been important for implementing improvements in the landscape of cardiac surgeries in the state of São Paulo. Although outcomes in cardiac surgery have improved due to the structuring and organization of quality programs, this is still not a reality at the national level. In a situation where data collection and quality initiatives play a central role in continuous improvement, generating value becomes essential for the sustainability of cardiac surgery programs. In this sense, the concept of Enhanced Recovery After Surgery (ERAS) has gained increasing traction. This concept is based on multidisciplinary protocols and scientific evidence, which help prepare patients for rapid recovery, resulting in reduced complications, shorter hospital stays, and, primarily, lower hospital costs. On the other hand, the increase in surgical waiting lists has also led to a rise in home mortality due to cardiac causes. Thus, among the various challenges imposed by the current scenario, the investigators believe that preparing patients for rapid recovery after coronary artery bypass grafting presents an opportunity for the sustainability of the healthcare system. Therefore, the aim of this project is to evaluate the impact of a technology platform based on ERAS on the postoperative recovery time of patients undergoing coronary artery bypass grafting in reference centers in the state of São Paulo, Timely Project - REPLICCAR III.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Standard care for CABG | No Intervention | Patients will be treated with CABG following the standard of care for each participant institution. | |
| ERACS with Digital Platform | Experimental | Patient will be treated by the participant institution following a modified protocol based in the ERACS with the aid of a digital platform. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ERACS with Digital Platform | Other | The assistance provided to patients in the intervention group will be sequential and prospective. The project will utilize an app based on protocols that prepare patients for rapid recovery (ERAS), starting before surgery and extending up to 30 days post-discharge. This includes pre-operative evaluations (dental, psychological, nutritional, and others), scheduling and confirming hospital admission, and following specific protocols during surgery and intensive care. The app aims to enhance communication and teamwork, improving patient-centered care. It will feature modules for patient and family education, team communication, and activity management through a dashboard. Additionally, it will facilitate interaction with patients through messages and surveys, monitor multidisciplinary team communication, and collect patient-reported outcomes 30 days after the surgical procedure. |
| Measure | Description | Time Frame |
|---|---|---|
| Lenght of Stay | Compare the length of stay after coronary artery bypass grafting (CABG) with versus without the use of a technology platform based on ERAS. | up to 30 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Percentage of Completeness of Protocol Steps | Compare adherence to protocol metrics through measure of the execution of the protocol steps by each participant center, during the intervention period. up to one week after surgery. | up to 01 week after surgery. |
| Morbility and Mortality |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Omar A V Mejia, MD, PhD | Contact | +551126615014 | omarvmejia@incor.usp.br | |
| Pedro H Reis, MD | Contact | +551126615014 | pedro.reis@fm.usp.br |
| Name | Affiliation | Role |
|---|---|---|
| Omar A V Mejia, MD, PhD | InCor - Instituto do Coração do Hospital das Clínicas da FMUSP | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| InCor - Instituto do Coração do Hospital das Clínicas da FMUSP | Recruiting | São Paulo | São Paulo | 05403-900 | Brazil | |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41474739 | Derived | Borgomoni GB, Reis PH, Pinheiro G, Ribas FF, Silva GSD, Campagnucci VP, Issa M, Farsky PS, Barg MM, Tiveron MG, Dos Reis Falcao LF, Dias RD, Ferreira Lisboa LA, Jatene FB, Mejia OAV. The technological proposal based on enhanced recovery after cardiac surgery for changing traditional care in Latin America: REPLICCAR III Study Protocol. PLoS One. 2025 Dec 31;20(12):e0338301. doi: 10.1371/journal.pone.0338301. eCollection 2025. |
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| Hospital Beneficence Portuguese of São Paulo |
| UNKNOWN |
| Irmandade Santa Casa Misericórdia Marília | OTHER |
| Faculdade de Medicina do ABC | OTHER |
Cluster Randomized Study
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Compare morbidity and mortality rates and hospital readmission between the control and intervention groups up to 6 months after CABG. |
| up to 6 months after surgery |
| Patient-reported outcomes (PROM) | Evaluate and patient-reported outcome measures following the questionnaire published by Ben-Ali W, Lamarche Y, Carrier M, Demers P, Bouchard D, El-Hamamsy I, et al. Use of Mobile-Based Application for Collection of Patient-Reported Outcomes in Cardiac Surgery. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery. 2021 Nov 1;16(6):536-44. at 01 month and 6 months after surgery. This questionary assess self reported pain, quality of recovery, anxiety and engagement of the patient with his/her recovery. | up to 6 months after surgery |
| Patient reported experience measure(PREM) | Assessment of patient experience using the Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) survey. | up to 6 months after surgery |
| InCor - Instituto do Coração do Hospital das Clínicas da FMUSP |
| Not yet recruiting |
| São Paulo |
| São Paulo |
| 05403-900 |
| Brazil |
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